M
Mengmeng Huang
Researcher at Chinese Academy of Sciences
Publications - 19
Citations - 660
Mengmeng Huang is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: C-type lectin & Pattern recognition receptor. The author has an hindex of 15, co-authored 19 publications receiving 521 citations. Previous affiliations of Mengmeng Huang include Zhejiang Sci-Tech University.
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Journal ArticleDOI
A novel C-type lectin from crab Eriocheir sinensis functions as pattern recognition receptor enhancing cellular encapsulation.
Leilei Wang,Lingling Wang,Daoxiang Zhang,Fengmei Li,Mengqiang Wang,Mengmeng Huang,Huan Zhang,Linsheng Song +7 more
TL;DR: REsCTL functioned as an important PRR involved in immune defense against invading pathogen in crab and could significantly enhance the in vitro encapsulation of crab hemocytes.
Journal ArticleDOI
The identification and characteristics of immune-related microRNAs in haemocytes of oyster Crassostrea gigas.
TL;DR: It is indicated that immune challenge could induce the expression of immune-related miRNAs, which might modulate the immune response such as redox reaction, phagocytosis and apoptosis, and some immune- related mi RNAs could be also regulated by heat stress to improve the environmental adaption of oyster.
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A multi-CRD C-type lectin with broad recognition spectrum and cellular adhesion from Argopectenirradians.
Leilei Wang,Lingling Wang,Jialong Yang,Huan Zhang,Mengmeng Huang,Pengfei Kong,Zhi Zhou,Linsheng Song +7 more
TL;DR: The recombinant AiCTL-9 could bind various PAMPs, including LPS, PGN, mannan and glucan, and also displayed agglutinating activity to fungi P. pastorisGS115, Gram-positive bacteria Bacillussubtilis and Gram-negative bacteria EscherichiacoliTOP10F' as well as V. anguillarum in a Ca(2+) dependent manner.
Journal ArticleDOI
A C-type lectin (AiCTL-3) from bay scallop Argopecten irradians with mannose/galactose binding ability to bind various bacteria
Mengmeng Huang,Xiaoyan Song,Xiaoyan Song,Jianmin Zhao,Changkao Mu,Lingling Wang,Huan Zhang,Zhi Zhou,Xiaolin Liu,Linsheng Song +9 more
TL;DR: The results clearly suggested that AiCTL-3 could serve not only as a PRR participated in the immune response against various PAMPs and bacteria in non-self recognition via mannose/galactose binding specificity but an opsonin playing an important part in clearance of invaders.
Journal ArticleDOI
A new fibrinogen-related protein from Argopecten irradians (AiFREP-2) with broad recognition spectrum and bacteria agglutination activity.
Chuanyan Yang,Leilei Wang,Huan Zhang,Lingling Wang,Mengmeng Huang,Zhibin Sun,Ying Sun,Linsheng Song +7 more
TL;DR: The results indicated that AiFREP-2 was involved in the immune response against Gram-negative bacteria, Gram-positive bacteria and fungus as a PRR in bay scallop, and the information was helpful to understand the innate immune defense mechanisms of mollusks.