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Showing papers in "Fish & Shellfish Immunology in 2013"


Journal ArticleDOI
TL;DR: An updated view on how teleost skin, gills and gut immune cells and molecules, function in response to pathogens and commensals is provided and some of the future avenues that the field of fish mucosal immunity may follow in the next years are highlighted.

527 citations


Journal ArticleDOI
TL;DR: This review summarizes the current status of the knowledge concerning the discovery and functional characterization of the immune molecules in penaeid shrimps.

367 citations


Journal ArticleDOI
TL;DR: This review highlights the recent discoveries of the critical roles of the proPO system in the shrimp immune responses against major pathogens, and emphasizes the functional characterizations of four major groups of genes and proteins in the pro PO cascade in penaeid shrimp, that is the PRPs, serine proteinases, proPO and inhibitors.

349 citations


Journal ArticleDOI
TL;DR: Study on the signaling pathway regulating the immune response in shrimp could help to understand the innate immune system, and would provide instructions to shrimp disease control.

291 citations


Journal ArticleDOI
TL;DR: The molecular, and increasing cellular, evidence for the existence of T-helper cells in fish is highlighted, and whether these cells will match exactly to the mammalian paradigm remains to be seen, but the early evidence suggests that there will be many similarities to known subsets.

260 citations


Journal ArticleDOI
TL;DR: Dietary supplementation of L. rohita is optimal for enhancing the growth, immunity, and disease resistance against A. hydrophila infection.

236 citations


Journal ArticleDOI
TL;DR: This paper will review the current use of licensed vaccines in fin fish farming and describe vaccine administration regimes including immersion, oral and injection vaccination and future trends for inactivated-, live attenuated - and DNA - vaccines will be discussed.

224 citations


Journal ArticleDOI
TL;DR: The present review aims to summarize the current knowledge on the PRRs of shrimp, which have been functionally studied and have been found to have different binding specificities and immune functions.

220 citations


Journal ArticleDOI
TL;DR: This review summarises previous studies performed with both traditional adjuvants as well as the most promising new generation adjuvant such as ligands for Toll receptors or different cytokines, focussing mostly on their protective efficacies.

217 citations


Journal ArticleDOI
TL;DR: B. amyloliquefaciens is a potential probiotic species and can be used in aquaculture to improve health status and disease resistance with an optimal dietary supplementation of 10(9) CFU/g.

173 citations


Journal ArticleDOI
TL;DR: Results suggest that the probiotic has a protective action on the intestinal mucosal cells, stimulating the innate immune response after feeding for a period of six weeks, and may potentiate the immune-responsiveness of the intestine.

Journal ArticleDOI
TL;DR: Dietary FOS and B. licheniformis could significantly enhance the innate immunity and antioxidant capability of triangular bream, as well as improve its disease resistance.

Journal ArticleDOI
TL;DR: Investigating early response mechanisms in the distal intestine of Atlantic salmon during the first week of oral exposure to a diet containing 20% extracted SBM resulted in rapid changes to the intestinal transcriptome, indicating an immune reaction with subsequent impaired epithelial barrier function and other vital intestinal functions.

Journal ArticleDOI
TL;DR: The results suggest that the synbiotic modulation of the gut microbiota has a protective action on the intestinal mucosal cells, improving morphology and stimulating the innate immune response without negatively affecting growth performance or feed utilization of farmed Atlantic salmon.

Journal ArticleDOI
TL;DR: The observed alterations demonstrate that fish fed experimental diets had different signs of gut oedema and inflammation that could compromise their body homeostasis, which is mainly maintained by the epithelial lining of the gastrointestinal tract.

Journal ArticleDOI
TL;DR: In this paper, the authors investigated the effects of administration of putative endogenous probiotics Lactococcus lactis spp. alone and in combination with arabinoxylan-oligosaccharides (AXOS), a new class of candidate prebiotics, in juvenile Siberian sturgeon (Acipenser baerii).

Journal ArticleDOI
TL;DR: An overview of the achievements in fish vaccinology is given with particular emphasis on immunoprophylaxis as a practical tool for a successful development of bioproduction of aquatic animals.

Journal ArticleDOI
TL;DR: This review summarizes and discusses recent results and developments in the field of T and NK cell responses with focus on economically important and experimental model fish species in the context of vaccination.

Journal ArticleDOI
TL;DR: It is suggested that fish fed neem leaf-supplemented diet improved the immune system and increased survival rate in L. calcarifer fingerlings against V. harveyi infection.

Journal ArticleDOI
TL;DR: The degree to which Lactobacillus strains adhere to the gut may be a favorable criterion in selecting probiotic strain for aquaculture.

Journal ArticleDOI
TL;DR: The results suggest that S. flavescens can be recommended as a tilapia feed supplement to enhance fish immunity and disease resistance against S. agalactiae.

Journal ArticleDOI
TL;DR: It is indicated that proper dietary lipid supplementation enhanced the immune response of grass carp and improved the survival rate in the bacterial challenge, but excess dietary lipid may elevate liver oxidation rates ofgrass carp.

Journal ArticleDOI
TL;DR: MHC IIA and IIB were probably two candidate immune molecules involved in the resistance against streptococcosis, because their expression was significantly up-regulated in gill, kidney, intestine and spleen after the intraperitoneal injection of Streptococcus agalactiae.

Journal ArticleDOI
TL;DR: The results suggest that ingestion of a basal diet supplemented with 240-480 mg/kg MOS can enhance resistance against pathogenic infections in Allogynogenetic crucian carp.

Journal ArticleDOI
TL;DR: Research efforts are now focused on the development of more effective vectors for DNA vaccines, improvement of vaccine efficacy against various viral diseases of fish for which there are currently no vaccines available and provision of co-expression of viral antigen and immunomodulatory compounds.

Journal ArticleDOI
TL;DR: It is indicated that dietary Ile improves the fish immune response, regulates the antioxidant status and cytokine, TOR and 4E-BP gene expression in the head kidney.

Journal ArticleDOI
TL;DR: The focus of this review is to relate aspects of immunity that are requisite for a mechanistic understanding of the generation of prophylactic immunity to the necessary analysis of responses to vaccines and vaccine candidates.

Journal ArticleDOI
TL;DR: Results indicated that dietary supplementation of FOS at a dose of 1% improved growth performance, beneficial intestinal microbiata and stimulate immune response of stellate sturgeon juvenile.


Journal ArticleDOI
TL;DR: Inactivated C. irritans vaccination improves specific and nonspecific immune responses in fish, enhancing their anti-parasite ability and are vaccine antigen dose-dependent.