M
Mette Boye
Researcher at Technical University of Denmark
Publications - 118
Citations - 4916
Mette Boye is an academic researcher from Technical University of Denmark. The author has contributed to research in topics: Necrotizing enterocolitis & Enterocolitis. The author has an hindex of 37, co-authored 117 publications receiving 4423 citations. Previous affiliations of Mette Boye include Aarhus University & University of Copenhagen.
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Journal ArticleDOI
Culture-independent analysis of gut bacteria: the pig gastrointestinal tract microbiota revisited.
Thomas D. Leser,Joanna Zeitman Amenuvor,Tim Kåre Jensen,R. H. Lindecrona,Mette Boye,Kristian Møller +5 more
TL;DR: The results document that the intestinal microbial community is very complex and that the majority of the bacterial species colonizing the gastrointestinal tract in pigs have not been characterized.
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Diet- and colonization-dependent intestinal dysfunction predisposes to necrotizing enterocolitis in preterm pigs
Per T. Sangild,Richard H. Siggers,Mette Schmidt,Jan Elnif,Charlotte R. Bjornvad,Thomas Thymann,Marie L. Grondahl,Axel Kornerup Hansen,Soeren K. Jensen,Mette Boye,Lars Moelbak,Randal K. Buddington,Björn Weström,Jens J. Holst,Douglas G. Burrin +14 more
TL;DR: Germ-free conditions and antiserum against Clostridium perfringens toxin prevented intestinal dysfunction and NEC in formula-fed pigs, whereas the gut trophic factors, epidermal growth factor, and glucagon-like peptide 2 had limited effects.
Journal ArticleDOI
The development of the gut microbiota in rainbow trout (Oncorhynchus mykiss) is affected by first feeding and diet type
Hans-Christian Ingerslev,L von Gersdorff Jørgensen,M. Lenz Strube,Niels Larsen,Inger Dalsgaard,Mette Boye,Lone Madsen +6 more
TL;DR: The results suggest that the intestine of rainbow trout is colonised at an early state, but is guided in new and different directions dependent on the diet type.
Journal ArticleDOI
Early Administration of Probiotics Alters Bacterial Colonization and Limits Diet-Induced Gut Dysfunction and Severity of Necrotizing Enterocolitis in Preterm Pigs
Richard H. Siggers,Jayda L Siggers,Mette Boye,Thomas Thymann,Lars Mølbak,Thomas D. Leser,Bent Borg Jensen,Per T. Sangild +7 more
TL;DR: It is suggested that probiotic administration immediately after birth promotes the colonization of a beneficial commensal microbiota capable of limiting the formula-induced mucosal atrophy, dysfunction, and pathogen load in preterm neonates, thereby reducing the incidence and severity of NEC.
Journal ArticleDOI
Enteral feeding induces diet-dependent mucosal dysfunction, bacterial proliferation, and necrotizing enterocolitis in preterm pigs on parenteral nutrition.
Charlotte R. Bjornvad,Thomas Thymann,Nicolaas E. P. Deutz,Douglas G. Burrin,Søren Krogh Jensen,Bent Borg Jensen,Lars Mølbak,Mette Boye,Lars-Inge Larsson,Mette Schmidt,Kim F. Michaelsen,Per T. Sangild +11 more
TL;DR: Enteral feeding is associated with gut dysfunction, microbial imbalance, and NEC in preterm pigs, especially in pigs fed formula after TPN, and colostrum milk diets improve gut maturation and NEC resistance in pre term pigs subjected to a few days of TPN after birth.