Mi-Ock Lee

TL;DR: RAR beta can mediate retinoid action in breast cancer cells by promoting apoptosis and loss of RAR beta, therefore, may contribute to the tumorigenicity of human mammary epithelial cells.

TL;DR: The observations raise the possibility that retinoic acid plays a role in the determination and maintenance of the dorsoventral axis of the retina, and that the morphogenetically significant asymmetry here lies in the spatial arrangement of synthetic pathways.

TL;DR: Evidence of a positive cross‐talk between HIF‐1α and MTA1, which is mediated by HDAC1 recruitment, is provided, and a close connection between MTA1‐associated metastasis and Hif‐1‐induced tumor angiogenesis is indicated.

TL;DR: It is shown that genistein increased expression of genes involved in lipid catabolism such as carnitine palmitoyltransferase 1, liver form in HepG2 cells, when assayed by real-time reverse-transcriptase polymerase chain reactions as well as Western blotting analysis.

TL;DR: It is demonstrated that expression of HIF-1α and vascular endothelial growth factor was increased in the liver of HBx-transgenic mice, suggesting that the cross-talk between HBx and hypoxia-inducible factor-1β may lead to transcriptional activation of Hif-1 α target genes, which play a critical role in hepatocarcinogenesis.