M
Michael A. Terzidis
Researcher at International Hellenic University
Publications - 58
Citations - 809
Michael A. Terzidis is an academic researcher from International Hellenic University. The author has contributed to research in topics: Chromone & One-pot synthesis. The author has an hindex of 15, co-authored 55 publications receiving 682 citations. Previous affiliations of Michael A. Terzidis include Aristotle University of Thessaloniki & New York University.
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Journal ArticleDOI
Purine 5′,8-cyclonucleoside lesions: chemistry and biology
TL;DR: The results reported for irradiated samples of calf thymus DNA have been critically reviewed, underlining the need of further research for the potential involvement of these lesions in human health.
Journal ArticleDOI
Structural basis for the recognition of diastereomeric 5′,8-cyclo-2′-deoxypurine lesions by the human nucleotide excision repair system
Konstantin Kropachev,Shuang Ding,Michael A. Terzidis,Annalisa Masi,Zhi Liu,Yuqin Cai,Marina Kolbanovskiy,Chryssostomos Chatgilialoglu,Suse Broyde,Nicholas E. Geacintov,Vladimir Shafirovich +10 more
TL;DR: The locally impaired stacking interaction energies correlate with relative NER incision efficiencies, and explain these results on a structural basis in terms of differences in dynamic perturbations of the DNA backbone imposed by the R and S covalent 5′,8 bonds.
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5',8-Cyclopurine Lesions in DNA Damage: Chemical, Analytical, Biological, and Diagnostic Significance.
Chryssostomos Chatgilialoglu,Carla Ferreri,Nicholas E. Geacintov,Marios G. Krokidis,Yuan Liu,Annalisa Masi,Vladimir Shafirovich,Michael A. Terzidis,Pawlos S. Tsegay +8 more
TL;DR: This review describes the main recent achievements in the preparation of the cPu molecular library for analytical and DNA synthesis applications for the studies of the enzymatic recognition and repair mechanisms, their impact on transcription and genetic instability, and quantitative determination of the levels of lesions in various types of cells and animal model systems.
Journal ArticleDOI
One-pot synthesis of functionalized spirobenzofuranones via MCR involving 3-cyanochromones.
Tryfon Zarganes-Tzitzikas,Michael A. Terzidis,Julia Stephanidou-Stephanatou,Constantinos A. Tsoleridis,George E. Kostakis +4 more
TL;DR: Another aspect concerning chromone chemistry leading to the one-pot synthesis of functionalized novel spirobenzofuranones has been described, and a plausible mechanistic rationale is proposed.
Journal ArticleDOI
One-pot synthesis of chromenylfurandicarboxylates and cyclopenta[b]chromenedicarboxylates involving zwitterionic intermediates. A DFT investigation on the regioselectivity of the reaction.
TL;DR: The reactants, intermediate zwitterions, transition structures, and intermediate products, leading to the final products, were optimized using the B3LYP functional with the 6-31G(d) basis set and the structures of the products were elucidated by 1D and 2D NMR experiments.