M
Michael Gösch
Researcher at École Polytechnique Fédérale de Lausanne
Publications - 17
Citations - 605
Michael Gösch is an academic researcher from École Polytechnique Fédérale de Lausanne. The author has contributed to research in topics: Fluorescence correlation spectroscopy & Fluorescence spectroscopy. The author has an hindex of 11, co-authored 17 publications receiving 577 citations. Previous affiliations of Michael Gösch include École Polytechnique.
Papers
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Journal ArticleDOI
First fully integrated 2-D array of single-photon detectors in standard CMOS technology
A. Rochas,Michael Gösch,Alexandre Serov,P.-A. Besse,Radivoje Popovic,Theo Lasser,Rudolf Rigler +6 more
TL;DR: In this paper, a two-dimensional array (4 by 8) of single-photon avalanche diodes integrated in an industrial complementary metal-oxide-semiconductor (CMOS) process is presented.
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Total internal reflection fluorescence correlation spectroscopy (TIR-FCS) with low background and high count-rate per molecule
Kai Hassler,Marcel Leutenegger,Per Rigler,Ramachandra Rao,Rudolf Rigler,Michael Gösch,Theo Lasser +6 more
TL;DR: A fluorescence correlation spectroscopy system for measurements on surfaces with an improvement in terms of counts per molecule and a high signal to background ratio is designed, demonstrated by investigating diffusion as well as binding and release of single molecules on a glass surface.
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High Count Rates with Total Internal Reflection Fluorescence Correlation Spectroscopy
TL;DR: It is shown that a new total internal reflection fluorescence correlation spectroscopy system based on an epi-illumination configuration achieves photon count rates per molecule as high as with commonly used confocal Fluorescence correlation Spectroscopy instruments.
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Confining the sampling volume for Fluorescence Correlation Spectroscopy using a sub-wavelength sized aperture
Marcel Dr. Leutenegger,Michael Gösch,A. Perentes,Patrik Hoffmann,Olivier J. F. Martin,Theo Lasser +5 more
TL;DR: A higher confinement of the sampling volume in the near-field of sub-wavelength sized apertures in a thin gold film is shown, indicating light confinement beyond the far-field diffraction limit.
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Simultaneous multicolor fluorescence cross-correlation spectroscopy to detect higher order molecular interactions using single wavelength laser excitation.
TL;DR: It is shown that SW-FCCS allows the simultaneous excitation of up to three fluorophores in which the cross correlation of their fluctuation signals is detected separately in three detection channels.