M
Michael Gregory Bell
Researcher at Eli Lilly and Company
Publications - 31
Citations - 622
Michael Gregory Bell is an academic researcher from Eli Lilly and Company. The author has contributed to research in topics: Receptor & Dyslipidemia. The author has an hindex of 10, co-authored 31 publications receiving 577 citations.
Papers
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Journal ArticleDOI
Activation of the GLP-1 receptor by a non-peptidic agonist
Peishen Zhao,Yi Lynn Liang,Matthew J. Belousoff,Giuseppe Deganutti,Madeleine M. Fletcher,Francis S. Willard,Michael Gregory Bell,Michael E. Christe,Kyle W. Sloop,Asuka Inoue,Tin T. Truong,Lachlan Clydesdale,Sebastian G.B. Furness,Arthur Christopoulos,Ming-Wei Wang,Ming-Wei Wang,Laurence J. Miller,Christopher A. Reynolds,Radostin Danev,Patrick M. Sexton,Patrick M. Sexton,Denise Wootten,Denise Wootten +22 more
TL;DR: The structure of a non-peptide agonist, TT-OAD2, bound to the glucagon-like peptide-1 (GLP-1) receptor is solved and alters the understanding of the events that drive the activation of class B receptors.
Journal ArticleDOI
Pharmacological characterization of LY335979: a potent cyclopropyldibenzosuberane modulator of P-glycoprotein.
James J. Starling,Robert L. Shepard,Jin Cao,Kevin L. Law,Bryan H. Norman,Julian Stanley Kroin,William J. Ehlhardt,Todd M. Baughman,Mark A. Winter,Michael Gregory Bell,Chuan Shih,Joseph Michael Gruber,William F. Elmquist,Anne H. Dantzig +13 more
TL;DR: The above data indicate that LY335979 is an exciting new clinical agent to test the hypothesis that inhibition of P-glycoprotein activity will result in reversal of multidrug resistance in human tumors.
Patent
Compounds and methods for modulating fxr
Michael Gregory Bell,Robert Anthony Doti,Matthew Scott Dowling,Michael James Genin,Peter Ambrose Lander,Tianwei Ma,Nathan Bryan Mantlo,Jason Matthew Ochoada,Lindsay Scott Stelzer,Ryan Edward Stites,Warshawsky Alan M +10 more
TL;DR: In this paper, a list of pharmaceutical compositions and methods of use for treating dyslipidemia and diseases related to it is presented. But none of them are described in detail.
Patent
Tricyclic steroid hormone nuclear receptor modulators
Michael J. Coghlan,Jonathan Edward Green,Timothy Alan Grese,Prabhakar Kondaji Jadhav,Donald P. Matthews,Mitchell I. Steinberg,Kevin Robert Fales,Michael Gregory Bell +7 more
TL;DR: In this article, a compound of the formula (I): or a pharmaceutically acceptable salt thereof; pharmaceutical compositions comprising an effective amount of a compound (I) in combination with a suitable carrier, diluent, or excipient; and methods for treating physiological disorders, particularly congestive heart disease, hypertension, rheumatoid arthritis or inflammation, comprising administering to a patient in thereof, a patient administered to a user in thereof an effective amounts of the compound of Formula (I).
Patent
Selective beta3 adrenergic agonists
Cynthia Darshini Jesudason,Donald P. Matthews,John H. McDonald,David Andrew Neel,Christopher John Rito,Anthony J. Shuker,Michael Gregory Bell,Thomas Alan Crowell,Droste Christine A,Mark A. Winter +9 more
TL;DR: In this article, selective β3 adrenergic receptor agonists useful in the treatment of Type II diabetes and obesity were presented in the field of medicine, particularly for Type II diabetic and obesity.