Michael Hauptmann

TL;DR: Assessment of PI3K pathway activation may provide a biomarker to identify patients unlikely to respond to trastuzumab-based therapy, and the combined analysis of PTEN and PIK3CA identified twice as many patients at increased risk for progression compared to PTEN alone.

TL;DR: The results imply that the correct classification of breast cancers of special histological type will allow a more accurate prognostication of breast cancer patients and facilitate the identification of optimal therapeutic strategies.

TL;DR: Findings challenge the National Council on Radiation Protection and International Commission on Radiological Protection assumptions that the lowest cumulative ionizing radiation dose to the lens of the eye that can produce a progressive cataract is approximately 2 Gy and support the hypothesis that the highest cataracts produced in humans is substantially less than previously thought.

TL;DR: The linear radiation dose-response relationship identified can be used to predictCHD risk for future HL patients and survivors and Appropriate early management of CHD risk factors and stimulation of physical activity may reduce CHDrisk in HL survivors.

TL;DR: In this cohort of formaldehyde-industry workers, some evidence was found of an exposure-response relation with mortality from nasopharyngeal cancer (based on small numbers) but not for cancers of the pancreas, brain, lung, or prostate.