M
Michael J. Berridge
Researcher at Babraham Institute
Publications - 222
Citations - 70299
Michael J. Berridge is an academic researcher from Babraham Institute. The author has contributed to research in topics: Inositol & Calcium. The author has an hindex of 100, co-authored 222 publications receiving 68051 citations. Previous affiliations of Michael J. Berridge include University of Cambridge.
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Journal ArticleDOI
The regulation of capacitative calcium entry by calcium and protein kinase C in Xenopus oocytes.
TL;DR: A variety of protocols revealed highly nonlinear behavior of the calcium entry in thapsigargin-treated oocytes suggestive of positive and negative feedback by calcium at the level of its own entry.
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Local and Global Spontaneous Calcium Events Regulate Neurite Outgrowth and Onset of GABAergic Phenotype during Neural Precursor Differentiation
Francesca Ciccolini,Francesca Ciccolini,Tony J. Collins,Juliana Sudhoelter,Peter Lipp,Michael J. Berridge,Martin D. Bootman +6 more
TL;DR: Spontaneous Ca2+ signals are an intrinsic property of differentiating neurosphere-derived precursors, and their frequency may specify neuronal morphology and acquisition of neurotransmitter phenotype.
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The spatial pattern of atrial cardiomyocyte calcium signalling modulates contraction
Lauren Mackenzie,H. Llewelyn Roderick,Michael J. Berridge,Stuart J. Conway,Martin D. Bootman +4 more
TL;DR: How calcium signals and their consequences are determined by the interplay of multiple subcellular calcium management systems is indicated.
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Calcium regulation of neural rhythms, memory and Alzheimer's disease
TL;DR: The persistent elevation in the resting level of Ca2+ induced by an accumulation of amyloid β (Aβ) oligomers duplicates a similar small global elevation normally restricted to the period of slow oscillations when memories are erased during sleep.
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Predetermined recruitment of calcium release sites underlies excitation-contraction coupling in rat atrial myocytes.
Lauren Mackenzie,Martin D. Bootman,Martin D. Bootman,Michael J. Berridge,Michael J. Berridge,Peter Lipp +5 more
TL;DR: It is concluded that rat atrial myocytes display a predetermined spatiotemporal pattern of Ca2+ signalling during early E‐C coupling, which reflects clusters of RyRs closely coupled to voltage‐operated Ca 2+ channels in the sarcolemma.