M
Michael J. Garlepp
Researcher at Curtin University
Publications - 57
Citations - 2293
Michael J. Garlepp is an academic researcher from Curtin University. The author has contributed to research in topics: Inclusion body myositis & Human leukocyte antigen. The author has an hindex of 24, co-authored 57 publications receiving 2217 citations. Previous affiliations of Michael J. Garlepp include University of Western Australia & Royal Perth Hospital.
Papers
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Journal ArticleDOI
Autoimmunity in ocular and generalised myasthenia gravis.
Michael J. Garlepp,Roger L. Dawkins,Frank T. Christiansen,J. Lawton,G. Luciani,James G. McLeod,J. Bradley,G. Genkins,C.S. Teng +8 more
TL;DR: It is suggested that different pathogenetic mechanisms are responsible for these two forms of MG.
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Sporadic inclusion body myositis: HLA-DRB1 allele interactions influence disease risk and clinical phenotype
Frank L. Mastaglia,Merrilee Needham,Adrian Scott,Ian James,P.J. Zilko,Timothy Day,L. Kiers,Alastair Corbett,Campbell S. Witt,Richard J.N. Allcock,Nigel G. Laing,Michael J. Garlepp,Frank T. Christiansen +12 more
TL;DR: Interactions between the HLA-DRB1*03 allele and other alleles at the DRB1 locus can influence disease susceptibility and the clinical phenotype in sIBM.
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Interleukin-12 induces an effective antitumor response in malignant mesothelioma.
Irina Caminschi,Eleni Venetsanakos,C.C. Leong,Michael J. Garlepp,Bernadette Scott,Bruce W. S. Robinson +5 more
TL;DR: IL-12 has potential in the immunotherapy of MM, through gene transfer or local cytokine administration, provided that significant intratumor levels of IL-12 can be achieved for prolonged periods.
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The immune anti-tumor effects of GM-CSF and B7-1 gene transfection are enhanced by surgical debulking of tumor
Sutapa Mukherjee,Delia J. Nelson,Suzanne Loh,Ivonne van Bruggen,Lyle J. Palmer,Lyle J. Palmer,C.C. Leong,Michael J. Garlepp,Bruce W. S. Robinson +8 more
TL;DR: Debulking surgery can augment the immunostimulatory effects of immunological gene therapy and can delay tumor growth, which has implications for the future design of human gene therapy trials for solid tumors such as MM.
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Apolipoprotein E ϵ4 in inclusion body myositis
TL;DR: In this paper, the ϵ4 allele of apolipoprotein E (APO E) has been strongly associated with familial and late-onset Alzheimer's disease (AD) and was found to be one of the factors involved in determining the predisposition to the development of inclusion body myositis.