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Michael J. Levene
Researcher at Yale University
Publications - 67
Citations - 4560
Michael J. Levene is an academic researcher from Yale University. The author has contributed to research in topics: Nucleic acid & Nucleic acid methods. The author has an hindex of 23, co-authored 67 publications receiving 4317 citations. Previous affiliations of Michael J. Levene include Cornell University & California Institute of Technology.
Papers
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Journal ArticleDOI
Zero-Mode Waveguides for Single-Molecule Analysis at High Concentrations
Michael J. Levene,Jonas Korlach,Stephen Turner,Mathieu Foquet,Harold G. Craighead,Watt W. Webb +5 more
TL;DR: It is shown that arrays of zero-mode waveguides consisting of subwavelength holes in a metal film provide a simple and highly parallel means for studying single-molecule dynamics at micromolar concentrations with microsecond temporal resolution.
Journal ArticleDOI
In Vivo Multiphoton Microscopy of Deep Brain Tissue
TL;DR: It is shown that multiphoton microscopy through GRIN lenses enables minimally invasive, subcellular resolution several millimeters in the anesthetized, intact animal, and it is presented in vivo images of cortical layer V and hippocampus in theAnesthetizing Thy1-YFP line H mouse.
Patent
Method for sequencing nucleic acid molecules
Jonas Korlach,Watt W. Webb,Michael J. Levene,Stephen Turner,Harold G. Craighead,Mathieu Foquet +5 more
TL;DR: In this paper, a method of sequencing a target nucleic acid molecule having a plurality of bases is proposed, in which a polymerase on the target DNA molecule complex is provided in a position suitable to move along the target molecule and extend the oligonucleotide primer at an active site.
PatentDOI
Holographic storage using shift multiplexing
TL;DR: In this article, the authors present a method of recording successive holograms in a recording medium, using at least a fan of M waves along at least one first axis with a separation angle between adjacent waves and directing the fan of the M waves as a reference beam along a reference path onto the recording medium.
Journal ArticleDOI
Shift multiplexing with spherical reference waves.
TL;DR: The performance of shift-multiplexed memories is characterized by using a spherical wave as the reference beam and the shift selectivity, the cross talk, the exposure schedule, and the storage density of the method are derived.