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Michael J. Pankratz
Researcher at University of Bonn
Publications - 37
Citations - 1120
Michael J. Pankratz is an academic researcher from University of Bonn. The author has contributed to research in topics: Neuromedin U & Neuropeptide. The author has an hindex of 16, co-authored 37 publications receiving 852 citations.
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Journal ArticleDOI
Synaptic transmission parallels neuromodulation in a central food-intake circuit
Philipp Schlegel,Michael J. Texada,Anton Miroschnikow,Andreas Schoofs,Sebastian Hückesfeld,Marc Peters,Casey M Schneider-Mizell,Haluk Lacin,Feng Li,Richard D. Fetter,James W Truman,Albert Cardona,Michael J. Pankratz +12 more
TL;DR: EM-based reconstruction is used to generate the entire connectome of hugin-producing neurons in the Drosophila larval CNS and shows that hugin neurons use synaptic transmission in addition to peptidergic neuromodulation and identify acetylcholine as a key transmitter.
Journal ArticleDOI
Genetic dissection of neural circuit anatomy underlying feeding behavior in Drosophila: Distinct classes of hugin‐expressing neurons
Rüdiger Bader,Julien Colomb,Bettina Pankratz,Anne Schröck,Reinhard F. Stocker,Michael J. Pankratz +5 more
TL;DR: The morphology of the hugin neurons at a single‐cell level is investigated by using clonal analysis and shows that single cells project to only one of the four major targets, which has functional implication for how they coordinate feeding behavior and growth.
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Single Serotonergic Neurons that Modulate Aggression in Drosophila
Olga V. Alekseyenko,Yick-Bun Chan,Maria Paz Fernandez,Torsten R. Bülow,Michael J. Pankratz,Edward A. Kravitz +5 more
TL;DR: In this article, the GAL4/upstreamactivating sequence (UAS) binary system with the Flippase (FLP) re-combination technique was used to restrict the number of targeted dopamine neurons down to a single-cell level.
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Selection of motor programs for suppressing food intake and inducing locomotion in the Drosophila brain.
Andreas Schoofs,Sebastian Hückesfeld,Philipp Schlegel,Anton Miroschnikow,Marc Peters,Malou Zeymer,Roland Spieß,Ann-Shyn Chiang,Michael J. Pankratz +8 more
TL;DR: This study reveals that a cluster of neurons expressing the neuropeptide hugin transmit inputs from higher brain centers to motor centers, thereby regulating feeding and locomotion in fruit fly larvae.
Journal ArticleDOI
The IGFBP7 homolog Imp-L2 promotes insulin signaling in distinct neurons of the Drosophila brain
R. Bader,Ladan Sarraf-Zadeh,M. Peters,Nina Moderau,Hugo Stocker,Katja Köhler,Michael J. Pankratz,Ernst Hafen +7 more
TL;DR: It is suggested that Imp-L2 acts as a licensing factor for neuronal IIS activation through Dilp-2 to further increase the precision of insulin activity in the brain.