M
Michael L. Alosco
Researcher at Boston University
Publications - 198
Citations - 7161
Michael L. Alosco is an academic researcher from Boston University. The author has contributed to research in topics: Chronic traumatic encephalopathy & Cognition. The author has an hindex of 39, co-authored 169 publications receiving 5233 citations. Previous affiliations of Michael L. Alosco include Rhode Island Hospital & VA Boston Healthcare System.
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Journal ArticleDOI
Clinicopathological Evaluation of Chronic Traumatic Encephalopathy in Players of American Football
Jesse Mez,Daniel H. Daneshvar,Patrick T. Kiernan,Bobak Abdolmohammadi,Victor E. Alvarez,Bertrand R. Huber,Michael L. Alosco,Todd M. Solomon,Christopher J. Nowinski,Lisa McHale,Kerry Cormier,Caroline A. Kubilus,Brett M. Martin,Lauren Murphy,Christine M. Baugh,Phillip H. Montenigro,Christine E. Chaisson,Yorghos Tripodis,Neil W. Kowall,Jennifer Weuve,Michael D. McClean,Robert C. Cantu,Lee E. Goldstein,Douglas I. Katz,Robert S. Stern,Thor D. Stein,Ann C. McKee +26 more
TL;DR: In a convenience sample of deceased football players who donated their brains for research, a high proportion had neuropathological evidence of CTE, suggesting that CTE may be related to prior participation in football.
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Cumulative Head Impact Exposure Predicts Later-Life Depression, Apathy, Executive Dysfunction, and Cognitive Impairment in Former High School and College Football Players
Philip H. Montenigro,Michael L. Alosco,Brett M. Martin,Daniel H. Daneshvar,Jesse Mez,Christine E. Chaisson,Christopher J. Nowinski,Rhoda Au,Ann C. McKee,Robert C. Cantu,McClean,Robert S. Stern,Yorghos Tripodis +12 more
TL;DR: A bivariate probit, instrumental variable model revealed a threshold dose-response relationship between the CHII and risk for later-life cognitive impairment, and greater predictive validity than other individual exposure metrics.
Journal ArticleDOI
Microglial neuroinflammation contributes to tau accumulation in chronic traumatic encephalopathy
Jonathan D. Cherry,Yorghos Tripodis,Victor E. Alvarez,Bertrand R. Huber,Patrick T. Kiernan,Daniel H. Daneshvar,Jesse Mez,Philip H. Montenigro,Todd M. Solomon,Michael L. Alosco,Robert S. Stern,Ann C. McKee,Thor D. Stein +12 more
TL;DR: RHI is associated with chronic activation of microglia, which may partially mediate the effect of RHI on the development of ptau pathology and dementia in CTE.
Journal ArticleDOI
Tau Positron-Emission Tomography in Former National Football League Players
Robert S. Stern,Charles H. Adler,Charles H. Adler,Kewei Chen,Michael Navitsky,Ji Luo,David W. Dodick,Michael L. Alosco,Yorghos Tripodis,Dhruman D. Goradia,Brett Martin,Diego Mastroeni,Nathan G. Fritts,Johnny Jarnagin,Michael D. Devous,Mark A. Mintun,Michael J. Pontecorvo,Martha E. Shenton,Martha E. Shenton,Martha E. Shenton,Eric M. Reiman +20 more
TL;DR: A group of living former NFL players with cognitive and neuropsychiatric symptoms had higher tau levels measured by PET than controls in brain regions that are affected by CTE and did not have elevated amyloid‐beta levels.
Journal ArticleDOI
Cognitive function after bariatric surgery: evidence for improvement 3 years after surgery
Michael L. Alosco,Rachel Galioto,Mary Beth Spitznagel,Mary Beth Spitznagel,Gladys W. Strain,Michael J. Devlin,Ronald A. Cohen,Ross D. Crosby,James E. Mitchell,John Gunstad,John Gunstad +10 more
TL;DR: Bariatiatric surgery may lead to lasting improvements in cognition, and Prospective studies with extended follow-ups should examine whether bariatric surgery can attenuate cognitive decline in severely obese patients.