M
Mark A. Mintun
Researcher at Avid Radiopharmaceuticals
Publications - 78
Citations - 6851
Mark A. Mintun is an academic researcher from Avid Radiopharmaceuticals. The author has contributed to research in topics: Dementia & Cognitive decline. The author has an hindex of 34, co-authored 78 publications receiving 5482 citations. Previous affiliations of Mark A. Mintun include Washington University in St. Louis.
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Journal ArticleDOI
Cerebral PET with florbetapir compared with neuropathology at autopsy for detection of neuritic amyloid-β plaques: a prospective cohort study
Christopher M. Clark,Michael J. Pontecorvo,Thomas G. Beach,Barry J. Bedell,R. Edward Coleman,P. Murali Doraiswamy,Adam S. Fleisher,Eric M. Reiman,Marwan N. Sabbagh,Carl H. Sadowsky,Julie A. Schneider,Anupa Arora,Alan Carpenter,Matthew Flitter,Abhinay D. Joshi,Michael J. Krautkramer,Ming Lu,Mark A. Mintun,Daniel Skovronsky +18 more
TL;DR: The results of this study validate the binary visual reading method approved in the USA for clinical use with flor betapir and suggest that florbetapir could be used to distinguish individuals with no or sparse amyloid plaques from those with moderate to frequent plaques.
Journal ArticleDOI
The Centiloid Project: Standardizing quantitative amyloid plaque estimation by PET
William E. Klunk,William E. Klunk,Robert A. Koeppe,Julie C. Price,Tammie L.S. Benzinger,Tammie L.S. Benzinger,Michael D. Devous,William J. Jagust,Keith A. Johnson,Chester A. Mathis,Davneet S. Minhas,Michael J. Pontecorvo,Christopher C. Rowe,Daniel Skovronsky,Mark A. Mintun +14 more
TL;DR: A working group was formed to standardize quantitative amyloid imaging measures by scaling the outcome of each particular analysis method or tracer to a 0 to 100 scale, anchored by young controls and typical Alzheimer's disease patients.
Journal ArticleDOI
Prevalence of amyloid PET positivity in dementia syndromes: a meta-analysis.
Rik Ossenkoppele,Willemijn J. Jansen,Gil D. Rabinovici,Dirk L. Knol,Wiesje M. van der Flier,Bart N.M. van Berckel,Philip Scheltens,Pieter Jelle Visser,Sander C.J. Verfaillie,Marissa D. Zwan,Sofie Adriaanse,Adriaan A. Lammertsma,Frederik Barkhof,William J. Jagust,Bruce L. Miller,Howard J. Rosen,Susan M. Landau,Victor L. Villemagne,Christopher C. Rowe,Dong Y. Lee,Duk L. Na,Sang W. Seo,Marie Sarazin,Catherine M. Roe,Osama Sabri,Henryk Barthel,Norman Koglin,John R. Hodges,Cristian E. Leyton,Rik Vandenberghe,Koen Van Laere,Alexander Drzezga,Stefan Förster,Timo Grimmer,Pascual Sánchez-Juan,José M. Carril,Vincent Mok,Vincent Camus,William E. Klunk,Ann D. Cohen,Philipp T. Meyer,Sabine Hellwig,Andrew B. Newberg,Kristian Steen Frederiksen,Adam S. Fleisher,Mark A. Mintun,David A. Wolk,Agneta Nordberg,Juha O. Rinne,Gaël Chételat,Alberto Lleó,Rafael Blesa,Juan Fortea,Karine Madsen,Karen M. Rodrigue,David J. Brooks +55 more
TL;DR: Findings indicate the potential clinical utility of amyloid imaging for differential diagnosis in early-onset dementia and to support the clinical diagnosis of participants with AD dementia and noncarrier APOE ε4 status.
Journal ArticleDOI
Amyloid-β Imaging with Pittsburgh Compound B and Florbetapir: Comparing Radiotracers and Quantification Methods
Susan M. Landau,Susan M. Landau,Susan M. Landau,Christopher Breault,Abhinay D. Joshi,Michael J. Pontecorvo,Chester A. Mathis,William J. Jagust,William J. Jagust,William J. Jagust,Mark A. Mintun +10 more
TL;DR: PiB and florbetapir retention ratios were strongly associated in the same individuals, and this relationship was consistent across several data analysis methods, despite scan–rescan intervals of more than a year.
Prevalence of Amyloid PET Positivity in Dementia Syndromes
Rik Ossenkoppele,Willemijn J. Jansen,Gil D. Rabinovici,Dirk L. Knol,Wiesje M. van der Flier,Bart N.M. van Berckel,Philip Scheltens,Pieter Jelle Visser,Sander C.J. Verfaillie,Marissa D. Zwan,Sofie Adriaanse,Adriaan A. Lammertsma,Frederik Barkhof,William J. Jagust,Bruce L. Miller,Howard J. Rosen,Susan M. Landau,Victor L. Villemagne,Christopher C. Rowe,Dong Y. Lee,Duk L. Na,Sang W. Seo,Marie Sarazin,Catherine M. Roe,Osama Sabri,Henryk Barthel,Norman Koglin,John R. Hodges,Cristian E. Leyton,Rik Vandenberghe,Koen Van Laere,Alexander Drzezga,Stefan Förster,Timo Grimmer,Pascual Sánchez-Juan,José M. Carril,Vincent Mok,Vincent Camus,William E. Klunk,Ann D. Cohen,Philipp T. Meyer,Sabine Hellwig,Andrew B. Newberg,Kristian Steen Frederiksen,Adam S. Fleisher,Mark A. Mintun,David A. Wolk,Agneta Nordberg,Juha O. Rinne,Gaël Chételat,Alberto Lleó,Rafael Blesa,Juan Fortea,Karine Madsen,Karen M. Rodrigue,David J. Brooks +55 more