Michael Levitt

TL;DR: This work introduces a method that adds specific information from known homologous structures but allows global and local deformations of these homology models, and gives significant improvements over conventional refinement in the model as monitored by coordinate accuracy, the definition of secondary structure and the quality of electron density maps.

TL;DR: A technique was developed to quantitate the absorption of ingested carbohydrate by means of continuous measurements of pulmonary H(2) excretion, which appears to provide quantitative information on carbohydrate malabsorption not readily obtained by presently available techniques.

TL;DR: The volume of atoms on the protein surface during a molecular-dynamics simulation of a small protein (pancreatic trypsin inhibitor) is analyzed using a particular geometric construction, called Voronoi polyhedra, that divides the total volume of the simulation box amongst the atoms, rendering them relatively larger or smaller depending on how tightly they are packed.

TL;DR: The results suggest that stabilization due to the effect of the crosslink on the entropy of the unfolded polypeptide is offset by the strain energy associated with formation of the disulfide bond in the folded protein.

TL;DR: A simple method for aligning protein sequences on the basis of a 3D structure, on a large scale, to the proteins in the scop classification of fold families is applied, with good agreement and detailed comparison highlights how particular protein structural features are problematical to align.