Michael Levitt

TL;DR: These studies suggest that the diarrhea observed in some postgastrectomy patients is, in part, the result of malabsorption of carbohydrate due to excessively rapid small bowel transit which is secondary to rapid gastric emptying.

TL;DR: The funnel and pore limitation on the rate of RNA synthesis under conditions of low NTP concentration may be overcome by NTP binding to an entry site adjacent to the active center.

TL;DR: Simulation of the wild-type pol II elongation complex and its mutants in explicit solvent found that the trigger loop is stabilized in the “closed” conformation, and His1085 forms a stable interaction with the NTP, and a three-component mechanism for correctly positioning the incoming NTP is suggested.

TL;DR: A simple yet powerful method for native fold recognition based on the tendency for native folds to form hydrophobic cores is developed, which yields energy values which are lowest for the population of structures generated at room temperature, intermediate for those produced at high temperature and highest for those constructed by threading methods.

TL;DR: The success of the density score and the self-RAPDF functions indicates that information from the ensemble of decoy conformations can be used to derive statistical probabilities and facilitate the identification of near-native structures.