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Michael Menaker

Researcher at University of Virginia

Publications -  206
Citations -  26979

Michael Menaker is an academic researcher from University of Virginia. The author has contributed to research in topics: Circadian rhythm & Light effects on circadian rhythm. The author has an hindex of 77, co-authored 206 publications receiving 25480 citations. Previous affiliations of Michael Menaker include University of Oregon & Mitsubishi Tanabe Pharma.

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Food-anticipatory activity and liver per1-luc activity in diabetic transgenic rats

TL;DR: In two separate experiments, FAA emerged and liver Per1 phase-shifted in response to daytime 8-h food restriction, which rule out insulin as a necessary component of this system.
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Deletion of TASK1 and TASK3 channels disrupts intrinsic excitability but does not abolish glucose or pH responses of orexin/hypocretin neurons

TL;DR: A novel role for TASK genes in enhancing neuronal excitability and promoting high‐frequency firing is supported, but it is suggested that TasK1/3 subunits are not essential for orexin cell responses to glucose and pH.
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Endogenous Rhythms of Body Temperature in Hibernating Bats

TL;DR: It is suggested that the endogenous “clock” may control the timing of the periodic arousals of bats during their winter hibernation.
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Circadian Clock in Photoperiodic Time Measurement: A Test of the Bünning Hypothesis

TL;DR: It has been shown that a 75-minute pulse of light per day is sufficient to produce a response normally produced only by long days in the sparrow Passer domesticus, and offers strong confirmation of B�nning's hypothesis concerning the mechanism of photoperiodic time measurement.
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Constitutive expression of the Period1 gene impairs behavioral and molecular circadian rhythms.

TL;DR: Molecular analysis revealed that the amplitudes of oscillation in the rat Per1 (rPer1) and rat Per2 ( rPer2) mRNAs were significantly attenuated in the SCN and eyes of the transgenic rats, indicating that the level of Per1, which is raised by overexpression, or its rhythmic expression, is critical for normal entrainment of behavior and molecular oscillation of other clock genes.