M
Michael O’Connell
Researcher at University of Pittsburgh
Publications - 53
Citations - 4781
Michael O’Connell is an academic researcher from University of Pittsburgh. The author has contributed to research in topics: Colorectal cancer & Oxaliplatin. The author has an hindex of 24, co-authored 53 publications receiving 4317 citations. Previous affiliations of Michael O’Connell include University of Rochester.
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Journal ArticleDOI
Oxaliplatin Combined With Weekly Bolus Fluorouracil and Leucovorin As Surgical Adjuvant Chemotherapy for Stage II and III Colon Cancer: Results From NSABP C-07
J. Philip Kuebler,H. Samuel Wieand,Michael O’Connell,Roy E. Smith,Linda H. Colangelo,Greg Yothers,N. J. Petrelli,Michael Findlay,Thomas E. Seay,James N. Atkins,John L. Zapas,J. Wendall Goodwin,Louis Fehrenbacher,Ramesh K. Ramanathan,Barbara A. Conley,Patrick J. Flynn,Gamini S. Soori,Lauren K. Colman,Edward A. Levine,Keith S. Lanier,Norman Wolmark +20 more
TL;DR: The addition of oxaliplatin to weekly FULV significantly improved DFS in patients with stage II and III colon cancer, and FLOX can be recommended as an effective option in clinical practice.
Journal ArticleDOI
Comparison of BISAP, Ranson's, APACHE-II, and CTSI scores in predicting organ failure, complications, and mortality in acute pancreatitis
Georgios I. Papachristou,Venkata Muddana,Dhiraj Yadav,Michael O’Connell,Michael K. Sanders,Adam Slivka,David C. Whitcomb +6 more
TL;DR: It is confirmed that the BISAP score is an accurate means for risk stratification in patients with AP and simple scoring systems may have reached their maximal utility and novel models are needed to further improve predictive accuracy.
Journal ArticleDOI
Alcohol Consumption, Cigarette Smoking, and the Risk of Recurrent Acute and Chronic Pancreatitis
Dhiraj Yadav,Robert H. Hawes,Randall E. Brand,Michelle A. Anderson,Mary E. Money,Peter A. Banks,Michele D. Bishop,John Baillie,Stuart Sherman,James A. DiSario,Frank R. Burton,Timothy B. Gardner,Stephen T. Amann,Andres Gelrud,Christopher Lawrence,Beth Elinoff,Julia B. Greer,Michael O’Connell,M. Michael Barmada,Adam Slivka,David C. Whitcomb +20 more
TL;DR: Very heavy alcohol consumption and smoking are independent risks for CP, and a minority of patients with pancreatitis currently seen at US referral centers report very heavy drinking.
Journal ArticleDOI
Relationship Between Tumor Gene Expression and Recurrence in Four Independent Studies of Patients With Stage II/III Colon Cancer Treated With Surgery Alone or Surgery Plus Adjuvant Fluorouracil Plus Leucovorin
Michael O’Connell,Ian C. Lavery,Greg Yothers,Soonmyung Paik,Kim M. Clark-Langone,Margarita Lopatin,Drew Watson,Frederick L. Baehner,Steven Shak,Joffre B. Baker,J. Wayne Cowens,Norman Wolmark +11 more
TL;DR: RT-qPCR of FPE colon cancer tissue applied to four large independent populations has been used to develop multigene algorithms for estimating recurrence risk and benefit from FU/LV.
Journal ArticleDOI
Natural History Following the First Attack of Acute Pancreatitis
TL;DR: The objective of this study was to determine the risk of recurrent AP (RAP) and subsequent chronic pancreatitis (CP) diagnosis after the first attack of AP and to suggest natural history of CP may be altered through early behavioral intervention.