Michael P. Barrett

TL;DR: In this paper, the authors used metabolomics to probe samples of CSF, plasma and urine from 40 Angolan patients infected with trypanosoma brucei gambiense, at different disease stages.

TL;DR: It is suggested that the lymphocyte infiltration of the meninges may later contribute to encephalitis, but have no evidence that the dural trypanosomes invade the parenchyma.

TL;DR: A versatile single complementary metal–oxide–semiconductor chip forming a platform to address personalized needs through on-chip multimodal optical and electrochemical detection that will reduce the number of tests that patients must take is presented.

TL;DR: Eflornithine should be the drug of choice for stage 2 disease, but resistance must be monitored.

TL;DR: This model provides insight into P2 transporter interactions with known compounds and contributes to strategies for the design of novel antiparasitic compounds and offers a quantitative and predictive tool for molecular recognition by specific transporters without the need for structural or even primary sequence information of the transport protein.