M
Michael P. Barrett
Researcher at University of Glasgow
Publications - 332
Citations - 15731
Michael P. Barrett is an academic researcher from University of Glasgow. The author has contributed to research in topics: Trypanosoma brucei & Metabolomics. The author has an hindex of 65, co-authored 318 publications receiving 13859 citations. Previous affiliations of Michael P. Barrett include University of Bordeaux & Wellcome Trust.
Papers
More filters
Morphology-based sorting-blood cells and parasites
TL;DR: The use of Deterministic Lateral Displacement is presented to create a chip-based, label-free diagnostic tool, capable of harvesting some of the wealth of information locked away in red blood cell morphology.
A high-throughput deterministic lateral displacement device for rapid and sensitive field-diagnosis of sleeping sickness
TL;DR: A simple and rapid microfluidic device capable of extracting and concentrating the parasite causing the fatal disease sleeping sickness from blood with a single inlet with flow induced by an ordinary syringe is presented.
Posted ContentDOI
Lipoic acid biosynthesis is essential for Plasmodium falciparum transmission and influences redox response and carbon metabolism of parasite asexual blood stages
Marco Biddau,Santha T.R. Kumar,Philipp P. Henrich,Larissa M. Laine,Gavin Blackburn,Achuthanunni Chokkathukalam,Tao Li,B. Kim Lee Sim,Stephen L. Hoffman,Michael P. Barrett,Graham H. Coombs,Geoffrey I. McFadden,David A. Fidock,Sylke Müller,Lilach Sheiner +14 more
TL;DR: Importantly, abrogation of LipB impacted P. falciparum mosquito development, preventing oocyst maturation and production of infectious sporozoite stages, thus flagging LA biosynthesis as a potential target for the development of new transmission drugs.
Journal ArticleDOI
Metabolomics on Integrated Circuit
TL;DR: A chip-based diagnostics tool for the quantification of metabolites, using specific enzymes, to study enzyme kinetics and calculate the Michaelis-Menten constant is demonstrated.