M
Michael Praktiknjo
Researcher at University Hospital Bonn
Publications - 131
Citations - 2374
Michael Praktiknjo is an academic researcher from University Hospital Bonn. The author has contributed to research in topics: Cirrhosis & Medicine. The author has an hindex of 19, co-authored 87 publications receiving 1143 citations. Previous affiliations of Michael Praktiknjo include University of Bonn.
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Journal ArticleDOI
Algorithm to rule out clinically significant portal hypertension combining Shear-wave elastography of liver and spleen: a prospective multicentre study
Christian Jansen,Christopher Bogs,Wim Verlinden,Maja Thiele,Philipp T. Möller,Jan Görtzen,Jennifer Lehmann,Michael Praktiknjo,Johannes Chang,Aleksander Krag,Christian P. Strassburg,Sven Francque,Jonel Trebicka +12 more
TL;DR: In this paper, a prospective multicentre study investigated the use of Shear-Wave elastography of the liver (L-SWE) as a promising tool to diagnose portal hypertension.
Journal ArticleDOI
Combined photodynamic therapy with systemic chemotherapy for unresectable cholangiocarcinoma.
Maria A. Gonzalez-Carmona,M Bolch,Christian Jansen,A Vogt,Matthias Sampels,Raphael Mohr,Katrin van Beekum,Robert Mahn,Michael Praktiknjo,Jacob Nattermann,Jonel Trebicka,Vittorio Branchi,Hanno Matthaei,Steffen Manekeller,Jörg C. Kalff,Christian P. Strassburg,Tobias J. Weismüller +16 more
TL;DR: Chemotherapy with gemcitabine and cisplatin is the current standard for patients with unresectable cholangiocarcinoma and local photodynamic therapy has also demonstrated benefit in patients with extrahepatic cholangsiocARCinoma.
Journal ArticleDOI
Acute decompensation boosts hepatic collagen type III deposition and deteriorates experimental and human cirrhosis.
Michael Praktiknjo,Jennifer Lehmann,Mette Juul Nielsen,Robert Schierwagen,Frank Erhard Uschner,Carsten H. Meyer,Daniel Thomas,Christian P. Strassburg,Flemming Bendtsen,Sören Möller,Aleksander Krag,Morten A. Karsdal,Diana Julie Leeming,Jonel Trebicka +13 more
TL;DR: It is shown for the first time that AD boosts collagen type III deposition in experimental and human Cirrhosis, possibly contributing to the worsened outcome in patients with decompensated cirrhosis.
Journal ArticleDOI
Role of portal venous platelet activation in patients with decompensated cirrhosis and TIPS
Alexander Queck,Roberto Carnevale,Frank Erhard Uschner,Robert Schierwagen,Sabine Klein,Christian Jansen,Carsten Meyer,Michael Praktiknjo,Daniel Thomas,Christian P. Strassburg,Stefan Zeuzem,Francesco Violi,Jonel Trebicka +12 more
TL;DR: TIPS placement is feasible for prevention of variceal rebleeding in the majority of cirrhotic patients with portal vein thrombosis and that it is more effective than endoscopic band ligation plus propranolol, but the prothrombotic milieu (platelet and plasmatic coagulation) has not been investigated to date.
Journal ArticleDOI
Controlled underdilation using novel VIATORR® controlled expansion stents improves survival after transjugular intrahepatic portosystemic shunt implantation
Michael Praktiknjo,J Abu-Omar,Johannes Chang,Daniel Thomas,Christian Jansen,Patrick Kupczyk,Filippo Schepis,Juan Carlos García-Pagán,Manuela Merli,Carsten Meyer,Christian P. Strassburg,Claus Christian Pieper,Jonel Trebicka +12 more
TL;DR: It is demonstrated that VCX stent grafts underdilated to 8 mm do not passively expand to nominal diameter and suggests reduced hospital readmissions because of hepatic encephalopathy, uncontrolled ascites, and heart failure, and improved 1-year survival compared with underdilation VTS.