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Christian P. Strassburg
Researcher at University Hospital Bonn
Publications - 509
Citations - 17836
Christian P. Strassburg is an academic researcher from University Hospital Bonn. The author has contributed to research in topics: Liver transplantation & Cirrhosis. The author has an hindex of 64, co-authored 453 publications receiving 15383 citations. Previous affiliations of Christian P. Strassburg include Wistar Institute & University of California, San Diego.
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Journal ArticleDOI
Human UDP-Glucuronosyltransferases: Metabolism, Expression, and Disease
TL;DR: Characterization of the UGT1A locus and genetic studies directed at understanding the role of bilirubin glucuronidation and the biochemical basis of the clinical symptoms found in unconjugated hyperbilirubinemia have uncovered the structural gene polymorphisms associated with Crigler-Najjar's and Gilbert's syndrome.
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Portopulmonary hypertension and hepatopulmonary syndrome
TL;DR: Criteria that allow improved prediction of which patients may, or may not, benefit from liver transplantation alone are provided, which are particularly challenging in patients who have severe pulmonary disease involvement.
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Patient Age, Sex, and Inflammatory Bowel Disease Phenotype Associate With Course of Primary Sclerosing Cholangitis
Tobias J. Weismüller,Tobias J. Weismüller,Palak J. Trivedi,Annika Bergquist,Mohamad Imam,Mohamad Imam,Henrike Lenzen,Cyriel Y. Ponsioen,Kristian Holm,Daniel Gotthardt,Martti Färkkilä,Hanns-Ulrich Marschall,Douglas Thorburn,Rinse K. Weersma,Johan Fevery,Tobias Mueller,Olivier Chazouillères,Kornelius Schulze,Konstantinos N. Lazaridis,Sven Almer,Stephen P. Pereira,Cynthia Levy,Andrew Mason,Sigrid Næss,Sigrid Næss,Christopher L. Bowlus,Annarosa Floreani,Emina Halilbasic,Kidist K. Yimam,Piotr Milkiewicz,Piotr Milkiewicz,Ulrich Beuers,Dep Huynh,Albert Parés,Christine N. Manser,George N. Dalekos,Bertus Eksteen,Pietro Invernizzi,Christoph P. Berg,Gabi I. Kirchner,Christoph Sarrazin,Vincent Zimmer,Luca Fabris,Felix Braun,Marco Marzioni,Brian D. Juran,Karouk Said,Christian Rupp,Kalle Jokelainen,Maria Benito de Valle,Francesca Saffioti,Angela Cheung,Michael Trauner,Christoph Schramm,Roger W. Chapman,Roger W. Chapman,Tom H. Karlsen,Tom H. Karlsen,Erik Schrumpf,Erik Schrumpf,Christian P. Strassburg,Michael P. Manns,Keith D. Lindor,Keith D. Lindor,Gideon M. Hirschfield,Bettina E. Hansen,Bettina E. Hansen,Bettina E. Hansen,Kirsten Muri Boberg,Kirsten Muri Boberg +69 more
TL;DR: In an analysis of data from individual patients with PSC worldwide, significant variation in clinical course associated with age at diagnosis, sex, and ductal and IBD subtypes is found.
Journal ArticleDOI
Budesonide induces remission more effectively than prednisone in a controlled trial of patients with autoimmune hepatitis
Michael P. Manns,Marek Woynarowski,Wolfgang Kreisel,Yoav Lurie,Christian Rust,Elimelech Zuckerman,Matthias J. Bahr,Rainer Günther,Rolf Hultcrantz,Ulrich Spengler,Ansgar W. Lohse,Ferenc Szalay,Martti Färkkilä,Markus Pröls,Christian P. Strassburg +14 more
TL;DR: Oral budesonide, in combination with azathioprine, induces and maintains remission in patients with noncirrhotic AIH, with a low rate of steroid-specific side effects.
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Assessment of biopsy-proven liver fibrosis by two-dimensional shear wave elastography: An individual patient data-based meta-analysis.
Eva Herrmann,Victor de Ledinghen,Christophe Cassinotto,Winnie C.W. Chu,Vivian Yee-Fong Leung,Giovanna Ferraioli,Carlo Filice,Laurent Castera,Valérie Vilgrain,Maxime Ronot,Jérôme Dumortier,Aymeric Guibal,Stanislas Pol,Jonel Trebicka,Christian Jansen,Christian P. Strassburg,Rongqin Zheng,Jian Zheng,Sven Francque,Thomas Vanwolleghem,Luisa Vonghia,Emanuel K. Manesis,Pavlos Zoumpoulis,Ioan Sporea,Maja Thiele,Aleksander Krag,Claude Cohen-Bacrie,Aline Criton,Thomas Deffieux,Mireen Friedrich-Rust +29 more
TL;DR: Two‐dimensional shear wave elastography has good to excellent performance for the noninvasive staging of liver fibrosis in patients with hepatitis B; further prospective studies are needed for head‐to‐head comparison between 2D‐SWE and other imaging modalities to establish disease‐specific appropriate cutoff points for assessment of fibrosis stage.