M
Michael Roth
Researcher at University Hospital of Basel
Publications - 251
Citations - 13038
Michael Roth is an academic researcher from University Hospital of Basel. The author has contributed to research in topics: Extracellular matrix & Platelet-derived growth factor receptor. The author has an hindex of 52, co-authored 232 publications receiving 11529 citations. Previous affiliations of Michael Roth include University of Southampton & Royal Prince Alfred Hospital.
Papers
More filters
Journal ArticleDOI
Are patients with hypertension and diabetes mellitus at increased risk for COVID-19 infection?
TL;DR: It is suggested that patients with cardiac diseases, hypertension, or diabetes, who are treated with ACE2increasing drugs, are at higher risk for severe COVID-19 infection and, therefore, should be monitored for ACE2-modulating medications, such as ACE inhibitors or ARBs.
Journal ArticleDOI
Hyaluronic acid: A key molecule in skin aging
TL;DR: Understanding the metabolism of HA in the different layers of the skin and the interactions of HA with other skin components will facilitate the ability to modulate skin moisture in a rational manner.
Journal ArticleDOI
Airway Smooth Muscle Cell Proliferation Is Increased in Asthma
Peter R. A. Johnson,Michael Roth,Michael Tamm,Margaret Hughes,Qi Ge,G.G. King,Janette K. Burgess,Judith L. Black +7 more
TL;DR: This study shows for the first time that proliferation of ASM cells is increased in patients with asthma and provides evidence for an intrinsic abnormality in the ASM cell in this disease.
Journal ArticleDOI
Corticosteroids inhibit the expression of the vascular endothelial growth factor gene in human vascular smooth muscle cells
TL;DR: The findings indicate that the capacity of corticosteroids to reduce edema or to prevent new blood vessel formation may be attributed, at least in part to the ability of these agents to abolish the expression of VEGF.
Journal ArticleDOI
Ligand-independent Activation of the Glucocorticoid Receptor by β2-Adrenergic Receptor Agonists in Primary Human Lung Fibroblasts and Vascular Smooth Muscle Cells
Oliver Eickelberg,Michael Roth,Rainer Lörx,Victoria Bruce,Jochen J. Rüdiger,Malcolm Johnson,Lutz-Henning Block +6 more
TL;DR: Data show that β2-AR agonists are potent activators of GR, and may substantially mediate the anti-inflammatory actions of these drugs observed in vitro and in vivo.