M
Michael Tamm
Researcher at University Hospital of Basel
Publications - 473
Citations - 19255
Michael Tamm is an academic researcher from University Hospital of Basel. The author has contributed to research in topics: COPD & Medicine. The author has an hindex of 63, co-authored 439 publications receiving 17529 citations. Previous affiliations of Michael Tamm include University of Basel.
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Journal ArticleDOI
Effect of procalcitonin-guided treatment on antibiotic use and outcome in lower respiratory tract infections: cluster-randomised, single-blinded intervention trial
Mirjam Christ-Crain,Daiana Jaccard-Stolz,Roland Bingisser,Mikael Gencay,Peter Huber,Michael Tamm,Beat Müller +6 more
TL;DR: Procalcitonin guidance substantially reduced antibiotic use in lower respiratory tract infections and could have important clinical and financial implications in view of the current overuse of antimicrobial therapy in often self-limiting acute respiratory tract infection.
Journal ArticleDOI
Procalcitonin guidance of antibiotic therapy in community-acquired pneumonia: a randomized trial.
Mirjam Christ-Crain,Daiana Stolz,Roland Bingisser,Christian Müller,David Miedinger,Peter Huber,Werner Zimmerli,Stéphan Juergen Harbarth,Michael Tamm,Beat Müller +9 more
TL;DR: Procalcitonin guidance substantially reduces antibiotic use in community-acquired pneumonia and may have important clinical and public health implications.
Journal ArticleDOI
Procalcitonin to initiate or discontinue antibiotics in acute respiratory tract infections
Philipp Schuetz,Yannick Wirz,Ramon Sager,Mirjam Christ-Crain,Daiana Stolz,Michael Tamm,Lila Bouadma,Charles Edouard Luyt,Michel Wolff,Jean Chastre,Florence Tubach,Kristina B. Kristoffersen,Olaf Burkhardt,Tobias Welte,Stefan Schroeder,Vandack Nobre,Long Wei,Heiner C. Bucher,Neera Bhatnagar,Djillali Annane,Konrad Reinhart,Angela Branche,Pierre Damas,Maarten W. N. Nijsten,Dylan W. de Lange,Rodrigo Octavio Deliberato,Stella Ss Lima,Vera Maravic-Stojkovic,Alessia Verduri,Bin Cao,Yahya Shehabi,Albertus Beishuizen,Jens-Ulrik Stæhr Jensen,Caspar Corti,Jos A H van Oers,Ann R. Falsey,Evelien de Jong,Carolina F. Oliveira,Bianca Beghe,Matthias Briel,Beat Mueller +40 more
TL;DR: In this article, a systematic review included individual patient data from 14 randomised controlled trials with a total of 4211 participants and found no increased risk for all-cause mortality or treatment failure when procalcitonin was used to guide initiation and duration of antibiotic treatment in participants with acute respiratory infections compared to control participants.
Journal ArticleDOI
Antibiotic Treatment of Exacerbations of COPD: A Randomized, Controlled Trial Comparing Procalcitonin-Guidance With Standard Therapy
Daiana Stolz,Mirjam Christ-Crain,Roland Bingisser,Jörg D. Leuppi,David Miedinger,Christian Müller,Peter Huber,Beat Müller,Michael Tamm +8 more
TL;DR: Procalcitonin guidance for exacerbations of COPD offers a sustained advantage over standard therapy in reducing antibiotic use for up to 6 months with a number-needed-to-treat of 3.
Journal ArticleDOI
Airway Smooth Muscle Cell Proliferation Is Increased in Asthma
Peter R. A. Johnson,Michael Roth,Michael Tamm,Margaret Hughes,Qi Ge,G.G. King,Janette K. Burgess,Judith L. Black +7 more
TL;DR: This study shows for the first time that proliferation of ASM cells is increased in patients with asthma and provides evidence for an intrinsic abnormality in the ASM cell in this disease.