M
Michael W. Barnhart
Researcher at Johns Hopkins University
Publications - 2
Citations - 2756
Michael W. Barnhart is an academic researcher from Johns Hopkins University. The author has contributed to research in topics: Genome-wide association study & Single-nucleotide polymorphism. The author has an hindex of 2, co-authored 2 publications receiving 2677 citations.
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A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants.
Laura J. Scott,Karen L. Mohlke,Lori L. Bonnycastle,Cristen J. Willer,Yun Li,William L. Duren,Michael R. Erdos,Heather M. Stringham,Peter S. Chines,Anne U. Jackson,Ludmila Prokunina-Olsson,Chia-Jen Ding,Amy J. Swift,Narisu Narisu,Tianle Hu,Randall Pruim,Rui Xiao,Xiao-Yi Li,Karen N. Conneely,Nancy Riebow,Andrew G. Sprau,Maurine Tong,Peggy P. White,Kurt N. Hetrick,Michael W. Barnhart,Craig W. Bark,Janet L. Goldstein,Lee Watkins,Fang Xiang,Jouko Saramies,Thomas A. Buchanan,Richard M. Watanabe,Timo T. Valle,Leena Kinnunen,Gonçalo R. Abecasis,Elizabeth W. Pugh,Kimberly F. Doheny,Richard N. Bergman,Jaakko Tuomilehto,Francis S. Collins,Michael Boehnke +40 more
TL;DR: The number of T2D loci now confidently identified to at least 10 is confirmed, and it is confirmed that variants near TCF7L2, SLC30A8, HHEX, FTO, PPARG, and KCNJ11 are associated with T1D risk.
Journal ArticleDOI
Investigation of altering single-nucleotide polymorphism density on the power to detect trait loci and frequency of false positive in nonparametric linkage analyses of qualitative traits.
Alison P. Klein,Ya Yu Tsai,Priya Duggal,Elizabeth M. Gillanders,Michael W. Barnhart,Rasika A. Mathias,Ian P. Dusenberry,Amy Turiff,Peter S. Chines,Janet L. Goldstein,Robert Wojciechowski,Wayne A. Hening,Elizabeth W. Pugh,Joan E. Bailey-Wilson +13 more
TL;DR: Their results showed that information content increased with increased map density, and for the homogeneous, completely penetrant traits the authors created, there was only a modest difference in ability to detect trait loci.