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Randall Pruim
Researcher at Calvin College
Publications - 47
Citations - 5641
Randall Pruim is an academic researcher from Calvin College. The author has contributed to research in topics: Polynomial hierarchy & Kolmogorov complexity. The author has an hindex of 11, co-authored 44 publications receiving 5146 citations. Previous affiliations of Randall Pruim include University of Michigan.
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Journal ArticleDOI
A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants.
Laura J. Scott,Karen L. Mohlke,Lori L. Bonnycastle,Cristen J. Willer,Yun Li,William L. Duren,Michael R. Erdos,Heather M. Stringham,Peter S. Chines,Anne U. Jackson,Ludmila Prokunina-Olsson,Chia-Jen Ding,Amy J. Swift,Narisu Narisu,Tianle Hu,Randall Pruim,Rui Xiao,Xiao-Yi Li,Karen N. Conneely,Nancy Riebow,Andrew G. Sprau,Maurine Tong,Peggy P. White,Kurt N. Hetrick,Michael W. Barnhart,Craig W. Bark,Janet L. Goldstein,Lee Watkins,Fang Xiang,Jouko Saramies,Thomas A. Buchanan,Richard M. Watanabe,Timo T. Valle,Leena Kinnunen,Gonçalo R. Abecasis,Elizabeth W. Pugh,Kimberly F. Doheny,Richard N. Bergman,Jaakko Tuomilehto,Francis S. Collins,Michael Boehnke +40 more
TL;DR: The number of T2D loci now confidently identified to at least 10 is confirmed, and it is confirmed that variants near TCF7L2, SLC30A8, HHEX, FTO, PPARG, and KCNJ11 are associated with T1D risk.
Journal ArticleDOI
LocusZoom: regional visualization of genome-wide association scan results
Randall Pruim,Ryan P. Welch,Serena Sanna,Tanya M. Teslovich,Peter S. Chines,Terry P. Gliedt,Michael Boehnke,Gonçalo R. Abecasis,Cristen J. Willer +8 more
TL;DR: LocusZoom is a web-based plotting tool that provides fast visual display of GWAS results in a publication-ready format that visually displays regional information such as the strength and extent of the association signal relative to genomic position, local linkage disequilibrium (LD) and recombination patterns and the positions of genes in the region.
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The mosaic Package: Helping Students to Think with Data Using R
TL;DR: An introduction to the mosaic package describes some of the guiding principles behind the design and provides illustrative examples of several of the most important functions it implements to help students “think with data" using R in their early course work.
Journal ArticleDOI
Tag SNP selection for Finnish individuals based on the CEPH Utah HapMap database
Cristen J. Willer,Laura J. Scott,Lori L. Bonnycastle,Anne U. Jackson,Peter S. Chines,Randall Pruim,Randall Pruim,Craig W. Bark,Ya-Yu Tsai,Elizabeth W. Pugh,Kimberly F. Doheny,Leena Kinnunen,Karen L. Mohlke,Timo T. Valle,Richard N. Bergman,Jaakko Tuomilehto,Jaakko Tuomilehto,Francis S. Collins,Michael Boehnke +18 more
TL;DR: The results demonstrate that the HapMap CEU samples provide an adequate basis for tag SNP selection in Finnish individuals, without the need to create a map specifically for the Finnish population, and suggest that the four‐population Hap map data will provide useful information for tag SNPs selection beyond the specific populations from which they were sampled.
Journal ArticleDOI
Determining Acceptance Possibility for a Quantum Computation is Hard for the Polynomial Hierarchy
TL;DR: It is shown that the complexity class NQP (a quantum analogue of NP) of Adleman, Demarrais and Huang, is equal to the counting class coC=P.