M
Michel Halbwax
Researcher at Max Planck Society
Publications - 10
Citations - 542
Michel Halbwax is an academic researcher from Max Planck Society. The author has contributed to research in topics: Pan paniscus & Gene. The author has an hindex of 7, co-authored 10 publications receiving 494 citations. Previous affiliations of Michel Halbwax include EcoHealth Alliance.
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Journal ArticleDOI
On the diversity of malaria parasites in African apes and the origin of Plasmodium falciparum from Bonobos.
Sabrina Krief,Ananias A. Escalante,M. Andreína Pacheco,Lawrence Mugisha,Claudine André,Michel Halbwax,Anne Fischer,Jean Michel Krief,John M. Kasenene,Mike Crandfield,Omar E. Cornejo,Jean Marc Chavatte,Clara Lin,Franck Letourneur,Anne Charlotte Grüner,Anne Charlotte Grüner,Thomas F. McCutchan,Laurent Rénia,Laurent Rénia,Georges Snounou +19 more
TL;DR: Phylogenetic analyses based on this diverse set of Plasmodium parasites in African Apes shed new light on the evolutionary history of P. falciparum, and indicated that chimpanzees and bonobos maintain malaria parasites, to which humans are susceptible, a factor of some relevance to the renewed efforts to eradicate malaria.
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Bonobos Fall within the Genomic Variation of Chimpanzees
Anne Fischer,Kay Prüfer,Jeffrey M. Good,Michel Halbwax,Victor Wiebe,Claudine André,Rebeca Atencia,Lawrence Mugisha,Susan E. Ptak,Svante Pääbo +9 more
TL;DR: While chimpanzees retain genomic variation that predates bonobo-chimpanzee speciation, extensive lineage sorting has occurred within bonobos such that much of their genome traces its ancestry back to a single common ancestor that postdates their origin as a group separate from chimpanzees.
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Long-Term Balancing Selection in LAD1 Maintains a Missense Trans-Species Polymorphism in Humans, Chimpanzees, and Bonobos
João C. Teixeira,Cesare de Filippo,Antje Weihmann,Juan R. Meneu,Fernando Racimo,Michael Dannemann,Birgit Nickel,Anne Fischer,Michel Halbwax,Claudine André,Rebeca Atencia,Matthias Meyer,Genís Parra,Svante Pääbo,Aida M. Andrés +14 more
TL;DR: This work sequenced the exome of 20 humans, 20 chimpanzees, and 20 bonobos and detected eight coding trans-species polymorphisms (trSNPs) that are shared among the three species and have segregated for approximately 14 My of independent evolution; the majority of these trSNPs were found in three genes of the major histocompatibility locus cluster, but one coding trSNP was uncovered in the gene LAD1.
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Bonobos have a more human-like second-to-fourth finger length ratio (2D:4D) than chimpanzees: a hypothesized indication of lower prenatal androgens.
Matthew H. McIntyre,Esther Herrmann,Victoria Wobber,Michel Halbwax,Crispin Mohamba,Nick de Sousa,Rebeca Atencia,Debby Cox,Brian Hare +8 more
TL;DR: It is hypothesized that the species difference in 2D:4D between bonobos and chimpanzees suggests a possible role for early exposure to sex hormones in the development of behavioral differences between the two species.
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Comparative Population Genomics of the Ejaculate in Humans and the Great Apes
Jeffrey M. Good,Victor Wiebe,Frank W. Albert,Hernán A. Burbano,Martin Kircher,Richard E. Green,Michel Halbwax,Claudine André,Rebeca Atencia,Anne Fischer,Svante Pääbo +10 more
TL;DR: The analyses indicate high levels of evolutionary constraint across much of the ejaculate combined with more rapid evolution of genes involved in immune defense and proteolysis, and general patterns of male reproductive protein evolution among apes and humans depend strongly on gene function but not on inferred differences in the intensity of sperm competition among extant species.