M
Michela Biancolella
Researcher at University of Rome Tor Vergata
Publications - 43
Citations - 1281
Michela Biancolella is an academic researcher from University of Rome Tor Vergata. The author has contributed to research in topics: Gene & Medicine. The author has an hindex of 13, co-authored 37 publications receiving 896 citations. Previous affiliations of Michela Biancolella include University of Southern California.
Papers
More filters
Journal ArticleDOI
Transcriptome-wide Regulation of Pre-mRNA Splicing and mRNA Localization by Muscleblind Proteins
Eric T. Wang,Neal A.L. Cody,Sonali P. Jog,Michela Biancolella,Thomas T. Wang,Daniel J. Treacy,Shujun Luo,Gary P. Schroth,David E. Housman,Sita Reddy,Eric Lécuyer,Christopher B. Burge +11 more
TL;DR: The muscle-blind-like (Mbnl) family of RNA-binding proteins plays important roles in muscle and eye development and in myotonic dystrophy (DM), in which expanded CUG or CCUG repeats functionally deplete Mbnl proteins as mentioned in this paper.
Journal ArticleDOI
HLA allele frequencies and susceptibility to COVID-19 in a group of 99 Italian patients.
Antonio Novelli,Marco Andreani,Michela Biancolella,Laura Liberatoscioli,Chiara Passarelli,Vito Luigi Colona,Paola Rogliani,Francesca Leonardis,Andrea Campana,Rita Carsetti,Massimo Andreoni,Sergio Bernardini,Giuseppe Novelli,Franco Locatelli +13 more
TL;DR: The increased frequencies observed may contribute to identify potential markers of susceptibility to the disease, although controversial results on the role of single HLA alleles in COVID‐19 patients have been recently reported.
Journal ArticleDOI
COVID-19 and Genetic Variants of Protein Involved in the SARS-CoV-2 Entry into the Host Cells.
Andrea Latini,Emanuele Agolini,Antonio Novelli,Paola Borgiani,Rosalinda Giannini,Paolo Gravina,Andrea Smarrazzo,Mario Dauri,Massimo Andreoni,Paola Rogliani,Sergio Bernardini,Manuela Helmer-Citterich,Michela Biancolella,Giuseppe Novelli +13 more
TL;DR: Genetic variants in these genes could influence the entry of the SARS-CoV-2 and support the hypothesis that host genetic variability may contribute to the variability in infection susceptibility and severity.
Journal ArticleDOI
Analysis of ACE2 genetic variants in 131 Italian SARS-CoV-2-positive patients.
Antonio Novelli,Michela Biancolella,Paola Borgiani,Dario Cocciadiferro,Vito Luigi Colona,Maria Rosaria D'Apice,Paola Rogliani,Salvatore Zaffina,Francesca Leonardis,Andrea Campana,Massimiliano Raponi,Massimo Andreoni,Sandro Grelli,Giuseppe Novelli +13 more
TL;DR: There is no strong evidence, in this cohort, of consistent association of ACE2 variants with COVID-19 severity, and it might speculate that rare susceptibility/resistant alleles could be located in the non-coding regions of the ACE2 gene, known to play a role in regulation of the gene activity.
Journal ArticleDOI
Gene expression analysis in myotonic dystrophy: indications for a common molecular pathogenic pathway in DM1 and DM2.
Annalisa Botta,Laura Vallo,Fabrizio Rinaldi,Emanuela Bonifazi,Francesca Amati,Michela Biancolella,Stefano Gambardella,E. Mancinelli,Corrado Angelini,Giovanni Meola,Giuseppe Novelli +10 more
TL;DR: The results indicate that the DM1 and DM2 overlapping clinical phenotypes may derive from a common trans acting mechanism that traps and influences shared genes and proteins.