Michela Roberto

TL;DR: Different mechanisms could be involved in sex differences with regard to immunotherapy and these differences could be relevant to identify immunological targets in order to draw studies exploring novel combinations of immunotherapy agents.

TL;DR: In this article, the main studies about clinical effects of several target inhibitors are reviewed, describing properly the most prominent mechanisms of both intrinsic and acquired resistance.

TL;DR: A nomogram based on easily available and inexpensive clinical factors showing a good performance in predicting individual OS probability among NSCLC patients treated with nivolumab is developed and could be valuable to clinicians in more accurately driving treatment decision in daily practice as well as enrollment onto clinical trials.

TL;DR: Lean body mass loss is associated with higher grade of toxicity in early breast cancer patients receiving adjuvant chemotherapy and L3 skeletal muscle index is an independent predictor of severe toxicity in multivariate analysis.

TL;DR: It is found that the presence of CTCs is associated with a reduced survival in colorectal cancer patients and further studies aimed at testing such a predictive value in early stage coloreCTal cancer are awaited.