Midori Kato-Negishi

TL;DR: Fibres encapsulating primary pancreatic islet cells and transplanted through a microcatheter into the subrenal capsular space of diabetic mice normalized blood glucose concentrations for about two weeks and may find use as templates for the reconstruction of fibre-shaped functional tissues that mimic muscle fibres, blood vessels or nerve networks in vivo.

TL;DR: The aim is to revisit the link between aluminum and AD and to integrate aluminum and amyloid cascade hypotheses in the context of β-amyloid oligomerization and the interactions with other metals.

TL;DR: Results indicate that the method succeeded in the formation of NMJs in the neuron-muscle construct system, which can potentially be used in pharmacokinetic assays related to NMJ disease therapies and in soft-robotic actuators.

TL;DR: It is demonstrated that fluid shear stress (FSS), an external mechanical cue, serves as a trigger for microvilli formation in human placental trophoblastic cells and it is revealed that the transient receptor potential, vanilloid family type-6 (TRPV6) calcium ion channel plays a critical role in flow-induced Ca2+ influx and microVilli formation.

TL;DR: A three-dimensional tissue with a neuronal network that can be easily manipulated and transplanted onto the host brain tissue in vivo is engineered and suggests that this method could lay the foundation for treating severe degenerative brain disease.