M
Mikael Skurnik
Researcher at University of Helsinki
Publications - 268
Citations - 13000
Mikael Skurnik is an academic researcher from University of Helsinki. The author has contributed to research in topics: Yersinia enterocolitica & Yersinia. The author has an hindex of 64, co-authored 254 publications receiving 12025 citations. Previous affiliations of Mikael Skurnik include University of Turku & University of Oslo.
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Journal ArticleDOI
Bacterial polysaccharide synthesis and gene nomenclature
Peter R. Reeves,Matthew Hobbs,Miguel A. Valvano,Mikael Skurnik,Chris Whitfield,David L. Coplin,Nobuo Kido,John D. Klena,Duncan J. Maskell,Christian R. H. Raetz,Paul D. Rick +10 more
TL;DR: This work proposes a scheme applicable to all species that distinguishes different classes of genes, provides a single name for all genes of a given function and greatly facilitates comparative studies.
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Pili-like proteins of Akkermansia muciniphila modulate host immune responses and gut barrier function
Noora Ottman,Noora Ottman,Noora Ottman,Justus Reunanen,Marjolein Meijerink,Taija E. Pietilä,Veera Kainulainen,Judith Klievink,Laura Huuskonen,Steven Aalvink,Mikael Skurnik,Mikael Skurnik,Sjef Boeren,Reetta Satokari,Annick Mercenier,Airi Palva,Hauke Smidt,Willem M. de Vos,Willem M. de Vos,Clara Belzer +19 more
TL;DR: Results indicate that outer membrane protein composition and particularly the newly identified highly abundant pili-like protein Amuc_1100 of A. muciniphila are involved in host immunological homeostasis at the gut mucosa, and improvement of gut barrier function.
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Phage therapy: Facts and fiction
Mikael Skurnik,Eckhard Strauch +1 more
TL;DR: The therapeutic use of bacteriophages, possibly in combination with antibiotics, may be a valuable approach but it is also quite clear that the safe and controlled use of phage therapy will require detailed information on the properties and behavior of specific phage-bacterium systems, both in vitro and especially in vivo.
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YadA, the multifaceted Yersinia adhesin.
Yasmin El Tahir,Mikael Skurnik +1 more
TL;DR: YadA is a multifaceted protein as revealed by its different biological properties, and in a rat model of reactive arthritis YadA and specifically YadA-mediated collagen binding is necessary for Y. enterocolitica to induce the disease.
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A Novel Erythromycin Resistance Methylase Gene (ermTR) in Streptococcus pyogenes
TL;DR: This work has identified a novelerm gene, designated ermTR, from an erythromycin-resistant clinical strain of S. pyogenes with an inducible type of MLSBresistance, which provides the first sequence of anerm gene other than ermAM that mediates MLSB resistance in S.pyogenes.