Miklós Tóth

TL;DR: It is shown that germ-free pregnant dams, devoid of maternal microbes, have offspring that show increased permeability of the blood-brain barrier, suggesting that crosstalk between the gut microbiota and the brain, initiated during the intrauterine period, is perpetuated throughout life.

TL;DR: The nanoScan integrated small-animal PET/MR imaging system has excellent spatial resolution and sensitivity and provides crucial advantages for preclinical imaging studies over existing PET/CT systems, especially in neurologic and oncologic research.

TL;DR: In vivo evidence that astrocytosis occurs early in AD, preceding Aβ plaque deposition is provided, and age-dependent increases in Aβ deposition in APPswe cortex and hippocampus are demonstrated.

TL;DR: PET studies using [(11)Cvinpocetine, as molecular imaging biomarker, can efficiently visualise the activation of microglia and the up-regulation of TSPO during ageing and in diseased brains with the help of an appropriate inhomogeneity analysis of the radioligand's brain uptake pattern.

TL;DR: Increased regional microglia activation, as a consequence of stroke, can be visualised with PET, using the TSPO molecular imaging biomarker [((11))C]vinpocetine, and shows a time dependent decrease the gradient of which is different between the peri-infarct zone and the ischaemic core.