Milan N. Stojanovic

TL;DR: It is demonstrated that previously developed random walkers show elementary robotic behaviour when interacting with a precisely defined environment and single-molecule microscopy observations confirm that such walkers achieve directional movement by sensing and modifying tracks of substrate molecules laid out on a two-dimensional DNA origami landscape.

TL;DR: A deoxyribonucleotide-based aptamer is adapted in two steps to signal the recognition of cocaine: an instability was engineered in one stem of a three-way junction that forms the cocaine-binding pocket and the resulting short stem was end labeled with a fluorophore and a quencher.

TL;DR: A molecular automaton, called MAYA, is described, which encodes a version of the game of tic-tac-toe and interactively competes against a human opponent and cannot be defeated because it implements a perfect strategy.

TL;DR: Sensing of charged and electroneutral targets (serotonin, dopamine, glucose, and sphingosine-1-phosphate) was enabled by specifically isolated aptameric stem-loop receptors, resulting in highly sensitive detection.

TL;DR: A set of deoxyribozyme-based logic gates capable of generating any Boolean function, constructed through a modular design that combines molecular beacon stem-loops with hammerhead-type deoxy ribozymes, open the possibility of communication between various computation elements in solution.