H
Hongyan Yang
Researcher at Semel Institute for Neuroscience and Human Behavior
Publications - 30
Citations - 1488
Hongyan Yang is an academic researcher from Semel Institute for Neuroscience and Human Behavior. The author has contributed to research in topics: Medicine & Chemistry. The author has an hindex of 12, co-authored 18 publications receiving 1032 citations. Previous affiliations of Hongyan Yang include University of California, Los Angeles & University of Michigan.
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Journal ArticleDOI
Aptamer–field-effect transistors overcome Debye length limitations for small-molecule sensing
Nako Nakatsuka,Kyung-Ae Yang,John M. Abendroth,Kevin M Cheung,Xiaobin Xu,Hongyan Yang,Chuanzhen Zhao,Bowen Zhu,You Seung Rim,Yang Yang,Paul S. Weiss,Milan N. Stojanovic,Anne M. Andrews,Anne M. Andrews +13 more
TL;DR: Sensing of charged and electroneutral targets (serotonin, dopamine, glucose, and sphingosine-1-phosphate) was enabled by specifically isolated aptameric stem-loop receptors, resulting in highly sensitive detection.
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Leptin Acts via Leptin Receptor-Expressing Lateral Hypothalamic Neurons to Modulate the Mesolimbic Dopamine System and Suppress Feeding
Gina M. Leinninger,Young Hwan Jo,Rebecca L. Leshan,Gwendolyn W. Louis,Hongyan Yang,Jason G. Barrera,Hilary Wilson,Darren M. Opland,Miro Faouzi,Yusong Gong,Justin C. Jones,Christopher J. Rhodes,Streamson C. Chua,Sabrina Diano,Tamas L. Horvath,Randy J. Seeley,Jill B. Becker,Heike Münzberg,Martin G. Myers +18 more
TL;DR: It is shown that leptin directly regulates a population of leptin receptor (LepRb)-expressing inhibitory neurons in the LHA and that leptin action via these LHA LepRb neurons decreases feeding and body weight in leptin-deficient animals.
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Disruption of the SH2-B Gene Causes Age-Dependent Insulin Resistance and Glucose Intolerance
TL;DR: The data suggest that SH2-B is a physiological enhancer of insulin receptor activation and is required for maintaining normal insulin sensitivity and glucose homeostasis during aging.
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Kappa Opioid Receptors Drive a Tonic Aversive Component of Chronic Pain.
Shiwei Liu,Sarah Pickens,Nicole E. Burma,Inés Ibarra-Lecue,Hongyan Yang,Lihua Xue,Christopher Cook,Joshua K. Hakimian,Amie L. Severino,Lindsay M. Lueptow,Kristina Komarek,Anna M.W. Taylor,Mary C. Olmstead,F. Ivy Carroll,Caroline E. Bass,Anne M. Andrews,Wendy Walwyn,Tuan Trang,Christopher J. Evans,Frances M. Leslie,Catherine M. Cahill +20 more
TL;DR: It is shown that KORs are sufficient to drive the tonic-aversive component of chronic pain; the emotional component of pain that is argued to significantly impact a patient's quality of life.
Journal ArticleDOI
Perinatal vs Genetic Programming of Serotonin States Associated with Anxiety
Stefanie C. Altieri,Hongyan Yang,Hannah J O'Brien,Hannah M. Redwine,Damla Şentürk,Julie G. Hensler,Anne M. Andrews,Anne M. Andrews +7 more
TL;DR: D dissimilarities in adult behavior and neurotransmission arising from developmental exposure to different widely prescribed antidepressants that are not recapitulated by genetic SERT insufficiency are revealed and support a pivotal role for serotonergic modulation of anxiety-related behavior.