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Mingfu Wu
Researcher at Huazhong University of Science and Technology
Publications - 37
Citations - 637
Mingfu Wu is an academic researcher from Huazhong University of Science and Technology. The author has contributed to research in topics: Metastasis & Cancer. The author has an hindex of 12, co-authored 34 publications receiving 534 citations.
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Journal ArticleDOI
Lymphoma endothelium preferentially expresses Tim-3 and facilitates the progression of lymphoma by mediating immune evasion
Xiaoyuan Huang,Xiangyang Bai,Yang Cao,Jingyi Wu,Mei Huang,Duozhuang Tang,Si Tao,Tao Zhu,Yanling Liu,Yang Yang,Xiaoxi Zhou,Yanxia Zhao,Mingfu Wu,Juncheng Wei,Dao Wen Wang,Gang Xu,Shixuan Wang,Ding Ma,Jianfeng Zhou +18 more
TL;DR: It is strongly argued that the lymphoma endothelium is not only a vessel system but also a functional barrier facilitating the establishment of lymphoma immune tolerance, which is a potential target for enhancing the efficacy of tumor immunotherapy and controlling metastatic diseases.
Journal ArticleDOI
Ezrin silencing by small hairpin RNA reverses metastatic behaviors of human breast cancer cells
Qiong Li,Mingfu Wu,Hui Wang,Gang Xu,Tao Zhu,Yongtao Zhang,Ping Liu,Anping Song,Chen Gang,Zhiqiang Han,Jianfeng Zhou,Li Meng,Yunpin Lu,Shixuan Wang,Ding Ma +14 more
TL;DR: Decreased ezrin expression by shRNA reversed metastatic behaviors of human breast cancer cells by inducing c-src-mediated E-cadherin expression, suggesting that eZrin may have potential values in assessing lymphatic metastasis of human Breast cancer cells.
Journal ArticleDOI
Tumor-associated Lymphatic Endothelial Cells Promote Lymphatic Metastasis by Highly Expressing and Secreting SEMA4C
Juncheng Wei,Jie Yang,Dan Liu,Mingfu Wu,Long Qiao,Junnai Wang,Quanfu Ma,Zhen Zeng,Shuangmei Ye,Ensong Guo,Xuefeng Jiang,Lanying You,Ying Chen,Li Zhou,Xiaoyuan Huang,Tao Zhu,Li Meng,Jianfeng Zhou,Zuo-Hua Feng,Ding Ma,Qinglei Gao +20 more
TL;DR: The results suggest that SEMA4C and RHOA might be potential therapeutic targets, and that higher serum sSEM4C could be a marker for breast cancer and cervical cancer.
Journal ArticleDOI
Mesenchymal stem cells as carriers and amplifiers in CRAd delivery to tumors
Xi Xia,Xi Xia,Teng Ji,Pingbo Chen,Xiao Li,Xiao Li,Yong Fang,Qinglei Gao,Shujie Liao,Lanying You,Hongbin Xu,Quanfu Ma,Peng Wu,Wencheng Hu,Mingfu Wu,Li Cao,Kezhen Li,Yanjie Weng,Zhiqiang Han,Junchen Wei,Ronghua Liu,Shixuan Wang,Gang Xu,Dao Wen Wang,Jianfeng Zhou,Ding Ma +25 more
TL;DR: Results indicate that MSCs migrate to the tumor site in a time-dependent manner and could be an effective platform for the targeted delivery of CRAd and the amplification of tumor killing effects.
Journal ArticleDOI
Soluble B and T lymphocyte attenuator possesses antitumor effects and facilitates heat shock protein 70 vaccine-triggered antitumor immunity against a murine TC-1 cervical cancer model in vivo.
Lingfei Han,Wei Wang,Yong Fang,Zuo-Hua Feng,Shujie Liao,Wei Li,Yan Li,Chunxiao Li,Mayinuer Maitituoheti,Dong Hong,Zhiwen Lai,Qinglei Gao,Ling Xi,Mingfu Wu,Dao Wen Wang,Jianfeng Zhou,Li Meng,Shixuan Wang,Ding Ma +18 more
TL;DR: Blocking the BTLA-HVEM interaction with sBTLA enhances antitumor efficacy and results in a significant synergistic effect against existent tumor cells in vivo when combined with the HSP70 vaccine.