Xiaoyuan Huang

TL;DR: It is strongly argued that the lymphoma endothelium is not only a vessel system but also a functional barrier facilitating the establishment of lymphoma immune tolerance, which is a potential target for enhancing the efficacy of tumor immunotherapy and controlling metastatic diseases.

TL;DR: This study finds that Tim-3 was expressed at a higher level in the clinical cervical cancer cells compared to the CIN and chronic cervicitis controls and suggests that the expression ofTim-3 in tumor cells may be an independent prognostic factor for patients with cervical cancer.

TL;DR: The data demonstrate that BK channels play an important role in regulating proliferation of human ovarian cancer cells and may induce apoptosis through induction of p21(Cip1) expression in a p53-dependent manner and NS1619 inhibits the proliferation of A2780 cells in a dosage and time dependent manner.

TL;DR: The results suggest that SEMA4C and RHOA might be potential therapeutic targets, and that higher serum sSEM4C could be a marker for breast cancer and cervical cancer.

TL;DR: Although there is no clear statistical significance indicates that ICIs are more effective in virus-associated cancers than non-virus infections, the efficacy of checkpoint inhibitors in the treatment of virus-related cancers is promising and provides a good direction for the implementation of individualized precision medicine.