M
Minkyoung Lee
Researcher at Ohio Agricultural Research and Development Center
Publications - 5
Citations - 342
Minkyoung Lee is an academic researcher from Ohio Agricultural Research and Development Center. The author has contributed to research in topics: Computer science & Medicine. The author has an hindex of 1, co-authored 2 publications receiving 285 citations.
Papers
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Journal ArticleDOI
In Planta Expression Screens of Phytophthora infestans RXLR Effectors Reveal Diverse Phenotypes, Including Activation of the Solanum bulbocastanum Disease Resistance Protein Rpi-blb2
Sang-Keun Oh,Sang-Keun Oh,Carolyn A. Young,Minkyoung Lee,Ricardo Oliva,Tolga O. Bozkurt,Liliana M. Cano,Joe Win,Jorunn I. B. Bos,Hsin-Yin Liu,Mireille van Damme,William Morgan,Doil Choi,Edwin A. G. van der Vossen,Vivianne G. A. A. Vleeshouwers,Sophien Kamoun,Sophien Kamoun +16 more
TL;DR: The Irish potato famine pathogen Phytophthora infestans is predicted to secrete hundreds of effector proteins and it is revealed that 16 of the 62 examined effectors cause phenotypes when expressed inside plant cells, and structure-function experiments indicated that a 34–amino acid region in the C-terminal half of AVRblb2 is sufficient for triggering Rpi-blb 2 hypersensitivity.
Journal ArticleDOI
Combining single-cell tracking and omics improves blood stem cell fate regulator identification
Arne Wehling,Dirk Loeffler,Yang Zhang,Tobías Kull,Cinzia Donato,Barbara Maria Szczerba,Germán Camargo Ortega,Minkyoung Lee,Andreas E. Moor,Bertie Gottgens,Nicola Aceto,Timm Schroeder +11 more
TL;DR: Using asymmetrically dividing blood stem cells, a pipeline is developed for imaging, tracking, isolating and transcriptome sequencing of single cells, massively improving molecular noise filtering and candidate identification.
Book ChapterDOI
Structure and Function of RXLR Effectors of Plant Pathogenic Oomycetes
William Morgan,Jorunn I. B. Bos,Catherine R. Bruce,Minkyoung Lee,Hsin-Yen Liu,Sang-Keun Oh,Jing Song,Joe Win,Carolyn A. Young,Sophien Kamoun +9 more
TL;DR: Little is known about the biology of effectors of eukaryoticplant pathogens, but progress has been made in elucidating the viru-lence functions of bacterial effectors and the biochemical activities that enable theseproteins to perturb host defense processes and facilitate pathogenicity.
Journal ArticleDOI
Development of Lumen-Based Perfusable 3D Liver in Vitro Model Using Single-Step Bioprinting with Composite Bioinks
In vivo single-cell CRISPR uncovers distinct TNF-α programs in clonal expansion and tumorigenesis
Peter Renz,Umesh Ghoshdastider,Simona Baghai Sain,Fabiola Valdivia-Francia,Mark L. Ormiston,Martino Bernasconi,Jonas A. Kretz,Minkyoung Lee,Merima Forny,Xenia Ficht,Stephanie J. Ellis,Andreas E. Moor,Ataman Sendoel +12 more
TL;DR: In this paper , the authors developed an in vivo single-cell CRISPR strategy to systematically investigate tissue-wide clonal dynamics of the 150 most frequently mutated squamous cell carcinoma genes.