M
Mirco Castoldi
Researcher at Heidelberg University
Publications - 30
Citations - 6201
Mirco Castoldi is an academic researcher from Heidelberg University. The author has contributed to research in topics: microRNA & Gene expression. The author has an hindex of 18, co-authored 23 publications receiving 5779 citations. Previous affiliations of Mirco Castoldi include Molecular Medicine Partnership Unit & University of Düsseldorf.
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Journal ArticleDOI
miRNAs in multiple myeloma--a survival relevant complex regulator of gene expression.
Anja Seckinger,Tobias Meißner,Jérôme Moreaux,Vladimir Benes,Jens Hillengass,Mirco Castoldi,Jürgen Zimmermann,Anthony D. Ho,Anna Jauch,Hartmut Goldschmidt,Bernard Klein,Dirk Hose +11 more
TL;DR: The myeloma-miRNome confers a pattern of small changes of individual miRNAs impacting on gene-expression, biological functions, and survival.
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Regulation of iron homeostasis by microRNAs
TL;DR: This review summarizes recent advances how miRNAs regulate iron homeostasis and describes how microRNAs control genes involved in some of these processes adding an additional level of complexity to the regulation of iron metabolism.
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AAV8-Mediated In Vivo Overexpression of miR-155 Enhances the Protective Capacity of Genetically Attenuated Malarial Parasites
Franziska Hentzschel,Christiane Hammerschmidt-Kamper,Kathleen Börner,Kirsten Heiss,Bettina Knapp,Julia M. Sattler,Lars Kaderali,Mirco Castoldi,Julia G. Bindman,Y Malato,Holger Willenbring,Ann-Kristin Mueller,Dirk Grimm +12 more
TL;DR: This study comprehensively studied hepatic gene and miRNA expression in GAP-injected mice, and found both a broad activation of IFNγ-associated pathways and a significant increase of murine microRNA-155 (miR-155), that was especially pronounced in non-parenchymal cells including liver-resident macrophages.
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Intracellular microRNA profiles form in the Xenopus laevis oocyte that may contribute to asymmetric cell division
TL;DR: This work measures the intracellular distribution of 12 maternal microRNAs (miRNA) along the animal-vegetal axis of the Xenopus laevis oocyte using qPCR tomography and finds the miRNAs have distinct intrACEllular profiles that resemble two out of the three profiles the authors previously observed for mRNAs.
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Molecular Probe Data Base (MPDB)
Maria Giuseppina Campi,Mirco Castoldi,Paolo Romano,Eduardo Thüroff,Maria Assunta Manniello,B. Iannotta,G. Rondanina,T. Ruzzon,Leonardo Santi +8 more
TL;DR: This paper provides an update on the contents and structure, forms and mode of data distribution of the Molecular Probe Data Base (MPDB), a database that collects and provides on-line information on the sequence, target gene, applications and bibliographic references of synthetic oligonucleotides.