Mirela Paiva Vasconcelos-Moreno

TL;DR: A meta-analysis and meta-regression of studies comparing inflammatory markers between patients with PTSD and healthy controls found that use of psychotropic medication and presence of comorbid major depressive disorder were important moderators that might explain the inconsistency between results of previous studies.

TL;DR: The data suggest that the epigenetic modulation of the FK BP5 gene, along with increased FKBP51 levels, is associated with the GR hyporesponsiveness seen in BD patients, consistent with the notion that unaffected first-degree relatives of BD patients share biological factors that influence the disorder.

TL;DR: Add-on exercise is an efficacious treatment for severely depressed inpatients, improving their depressive symptoms and QoL, and initial acceptance of exercise remains a challenge.

TL;DR: The preliminary results suggest that physical exercise could be a feasible and effective add-on strategy for treatment of severe depressed inpatients, improving their depressive symptoms and QoL.

TL;DR: The present results suggest that unaffected siblings may present accelerated aging features and neurobiological findings may be considered as endophenotypic traits.