C
Carolina Gubert
Researcher at Florey Institute of Neuroscience and Mental Health
Publications - 45
Citations - 1222
Carolina Gubert is an academic researcher from Florey Institute of Neuroscience and Mental Health. The author has contributed to research in topics: Medicine & Gut flora. The author has an hindex of 16, co-authored 35 publications receiving 878 citations. Previous affiliations of Carolina Gubert include Universidade Federal do Rio Grande do Sul.
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Journal ArticleDOI
Exercise, diet and stress as modulators of gut microbiota: Implications for neurodegenerative diseases
TL;DR: The evidence for environmental modulation of gut microbiota and its relevance to brain disorders is reviewed, exploring in particular the implications for neurodegenerative diseases.
Journal ArticleDOI
Hypothalamic-pituitary-adrenal axis dysfunction and illness progression in bipolar disorder.
Gabriel Rodrigo Fries,Mirela Paiva Vasconcelos-Moreno,Carolina Gubert,Bárbara Tietbohl Martins Quadros dos Santos,Juliana Sartori,Barbara Eisele,Pamela Ferrari,Adam Fijtman,Joëlle Rüegg,Nils C. Gassen,Flávio Kapczinski,Theo Rein,Márcia Kauer-Sant'Anna +12 more
TL;DR: The data suggest that the epigenetic modulation of the FK BP5 gene, along with increased FKBP51 levels, is associated with the GR hyporesponsiveness seen in BD patients, consistent with the notion that unaffected first-degree relatives of BD patients share biological factors that influence the disorder.
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Mitochondrial activity and oxidative stress markers in peripheral blood mononuclear cells of patients with bipolar disorder, schizophrenia, and healthy subjects
Carolina Gubert,Laura Stertz,Bianca Pfaffenseller,Bruna Panizzutti,Gislaine T. Rezin,Raffael Massuda,Emilio L. Streck,Clarissa Severino Gama,Flávio Kapczinski,Maurício Kunz +9 more
TL;DR: The results suggest that mitochondrial complex I dysfunction and oxidative stress play important roles in the pathophysiology of SZ and may be used in potential novel adjunctive therapy for SZ, focusing primarily on cognitive impairment and disorder progression.
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Effects of omega-3 dietary supplement in prevention of positive, negative and cognitive symptoms: A study in adolescent rats with ketamine-induced model of schizophrenia
Clarissa Severino Gama,Lara Canever,Bruna Panizzutti,Carolina Gubert,Laura Stertz,Raffael Massuda,Mariana Pedrini,David Freitas de Lucena,Renata D. De Luca,Daiane B. Fraga,Alexandra S. Heylmann,Pedro F. Deroza,Alexandra I. Zugno +12 more
TL;DR: In this paper, the efficacy of Omega-3 in preventing ketamine-induced effects in an animal model of schizophrenia and its effect on brain-derived neurotrophic factor (BDNF) was evaluated.
Journal ArticleDOI
Ketamine and imipramine in the nucleus accumbens regulate histone deacetylation induced by maternal deprivation and are critical for associated behaviors.
Gislaine Z. Réus,Helena M. Abelaira,Maria Augusta B Dos Santos,Anelise S. Carlessi,Débora B. Tomaz,Morgana V. Neotti,João Lucas Garcia Liranço,Carolina Gubert,Maurício Barth,Flávio Kapczinski,João Quevedo +10 more
TL;DR: A novel insight is provided into the epigenetic regulation of histone deacetylase in the nucleus accumbens caused by imipramine and ketamine, and indicate that molecular events are necessary to reverse specific stress-induced behavior.