M
Mitali Mukerji
Researcher at Institute of Genomics and Integrative Biology
Publications - 124
Citations - 4056
Mitali Mukerji is an academic researcher from Institute of Genomics and Integrative Biology. The author has contributed to research in topics: Population & Gene. The author has an hindex of 27, co-authored 113 publications receiving 3454 citations. Previous affiliations of Mitali Mukerji include Academy of Scientific and Innovative Research & Central Food Technological Research Institute.
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Journal ArticleDOI
Ancestral Variations of the PCDHG Gene Cluster Predispose to Dyslexia in a Multiplex Family.
Teesta Naskar,Mohammed Faruq,P Banerjee,Massarat Khan,Rashi Midha,Renu Kumari,Subhashree Devasenapathy,Bharat Prajapati,Sanghamitra Sengupta,Deepti Jain,Mitali Mukerji,Nandini Chatterjee Singh,Subrata Sinha,Subrata Sinha +13 more
TL;DR: The observed association of PCDHG genes encoding neural adhesion proteins reinforces the hypothesis of aberrant neuronal connectivity in the pathophysiology of dyslexia and the striking conservation of the identified variants indicates a role of PC DHG in the evolution of highly specialized cognitive skills critical to reading.
A rigorous framework for detecting SARS-CoV-2 spike protein mutational ensemble from genomic and structural features.
Saman Fatihi,Saman Fatihi,Surabhi Rathore,Surabhi Rathore,Ankit K. Pathak,Deepanshi Gahlot,Deepanshi Gahlot,Mitali Mukerji,Mitali Mukerji,Nidhi Jatana,Lipi Thukral,Lipi Thukral +11 more
TL;DR: In this article, the authors temporally track 527,988 SARS-CoV-2 genomes and identify invariant and hypervariable regions within the spike protein and find that the maximum number of lineage-defining mutations were present in the N-terminal domain (NTD).
Journal ArticleDOI
Targeted exome sequencing in anti-factor H antibody negative HUS reveals multiple variations
Ranjeet Thergaonkar,Ankita Narang,Bahadur Singh Gurjar,Pradeep Kumar Tiwari,Mamta Puraswani,Himanshi Saini,Aditi Sinha,Binuja Varma,Mitali Mukerji,Pankaj Hari,Arvind Bagga +10 more
TL;DR: It is concluded that genetic testing for multiple genes in patients with aHUS negative for anti-FH antibodies reveals multiple candidate variations that require prioritization and population data on variation frequency of the Indian population and supportive functional studies are likely to improve diagnostic yield.
Posted ContentDOI
The impact of sex on alternative splicing
Guy Karlebach,Diogo F.T. Veiga,Anne Deslattes Mays,Anil K. Kesarwani,Daniel Danis,Georgios Kararigas,Xingmin Aaron Zhang,Joshy George,Guru Ananda,Robin Steinhaus,Peter Hansen,Dominik Seelow,Chris Bizon,Rebecca R. Boyles,Chris Ball,Julie A. McMurry,Melissa A. Haendel,Jeremy J. Yang,Tudor I. Oprea,Mitali Mukerji,Olga Anczuków,Jacques Banchereau,Peter N. Robinson +22 more
TL;DR: In this paper, the authors used hierarchical Bayesian modeling to characterize the interactions of exon skipping, gene expression, and RNA-binding proteins (RBPs), and demonstrate two categories of sex-biased alternative splicing events.
Journal ArticleDOI
Investigation of mitochondrial DNA variations among Indian Friedreich's ataxia (FRDA) patients.
Inder Singh,Mohammed Faruq,Madakasira V. Padma,Vinay Goyal,Madhuri Behari,Ashoo Grover,Mitali Mukerji,Achal Kumar Srivastava +7 more
TL;DR: This study identifies the functionally important variations and mitochondrial lineage of Indian FRDA cases and underscores the importance of studying the role of mitochondrial genome variations in FRDA.