M
Mohamad E. Allaf
Researcher at Johns Hopkins University School of Medicine
Publications - 390
Citations - 13393
Mohamad E. Allaf is an academic researcher from Johns Hopkins University School of Medicine. The author has contributed to research in topics: Nephrectomy & Renal cell carcinoma. The author has an hindex of 51, co-authored 367 publications receiving 10829 citations. Previous affiliations of Mohamad E. Allaf include American Urological Association & Cleveland Clinic.
Papers
More filters
Journal ArticleDOI
Renal Mass and Localized Renal Cancer: AUA Guideline
Steven C. Campbell,Robert G. Uzzo,Mohamad E. Allaf,Eric B Bass,Jeffrey A. Cadeddu,Anthony Chang,Peter E. Clark,Brian J. Davis,Ithaar Derweesh,Leo Giambarresi,Debra A. Gervais,Susie L. Hu,Brian R. Lane,Bradley C. Leibovich,Philip M. Pierorazio +14 more
TL;DR: Several factors should be considered during counseling/management of patients with clinically localized renal masses, including general health/comorbidities, oncologic potential of the mass, pertinent functional issues and relative efficacy/potential morbidities of various management strategies.
Journal ArticleDOI
Genomic correlates of response to immune checkpoint therapies in clear cell renal cell carcinoma
Diana Miao,Diana Miao,Claire A. Margolis,Claire A. Margolis,Wenhua Gao,Martin H. Voss,Martin H. Voss,Wei Li,Dylan J. Martini,Craig Norton,Dominick Bossé,Stephanie M. Wankowicz,Stephanie M. Wankowicz,Dana Cullen,Christine Horak,Megan Wind-Rotolo,Adam Tracy,Marios Giannakis,Marios Giannakis,F.S. Hodi,Charles G. Drake,Mark W. Ball,Mohamad E. Allaf,Alexandra Snyder,Matthew D. Hellmann,Matthew D. Hellmann,Thai H. Ho,Robert J. Motzer,Robert J. Motzer,Sabina Signoretti,William G. Kaelin,William G. Kaelin,Toni K. Choueiri,Eliezer M. Van Allen,Eliezer M. Van Allen +34 more
TL;DR: Clinical benefit was associated with loss-of-function mutations in the PBRM1 gene, which encodes a subunit of the PBAF switch-sucrose nonfermentable (SWI/SNF) chromatin remodeling complex, and may alter global tumor-cell expression profiles to influence responsiveness to immune checkpoint therapy.
Journal ArticleDOI
Anatomical extent of lymph node dissection: impact on men with clinically localized prostate cancer.
TL;DR: Compared to limited lymph node dissection, extended pelvic lymphadenectomy appears to identify men with positive lymph nodes more frequently and a significant benefit in biochemical recurrence-free survival may exist for certain subgroups undergoing the extended dissection.
Journal ArticleDOI
Management of Renal Masses and Localized Renal Cancer: Systematic Review and Meta-Analysis
Phillip M. Pierorazio,Michael H. Johnson,Hiten D. Patel,Stephen M. Sozio,Ritu Sharma,Emmanuel Iyoha,Eric B Bass,Mohamad E. Allaf +7 more
TL;DR: Comparative studies demonstrated similar cancer specific survival across management strategies, with some differences in renal functional outcomes, perioperative outcomes and postoperative harms that should be considered when choosing a management strategy.
Journal ArticleDOI
Five-year Analysis of a Multi-institutional Prospective Clinical Trial of Delayed Intervention and Surveillance for Small Renal Masses: The DISSRM Registry ☆
Phillip M. Pierorazio,Michael H. Johnson,Mark W. Ball,Michael A. Gorin,Bruce J. Trock,Peter Chang,Andrew A. Wagner,James M. McKiernan,Mohamad E. Allaf +8 more
TL;DR: In a well-selected cohort with up to 5 yr of prospective follow-up, AS was not inferior to PI and Discussion of active surveillance should become part of the standard discussion for management of small renal masses.