M
Mohammad F. Farooq
Researcher at University of New Hampshire
Publications - 2
Citations - 209
Mohammad F. Farooq is an academic researcher from University of New Hampshire. The author has contributed to research in topics: Heat shock protein & Ex vivo. The author has an hindex of 2, co-authored 2 publications receiving 160 citations. Previous affiliations of Mohammad F. Farooq include Memorial Sloan Kettering Cancer Center.
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The epichaperome is an integrated chaperome network that facilitates tumour survival
Anna Rodina,Tai Wang,Pengrong Yan,Erica DaGama Gomes,Mark Dunphy,Nagavarakishore Pillarsetty,John Koren,John F. Gerecitano,Tony Taldone,Hongliang Zong,Eloisi Caldas-Lopes,Mary L. Alpaugh,Adriana D. Corben,Matthew Riolo,Brad Beattie,Christina Pressl,Radu I Peter,Chao Xu,Robert Trondl,Hardik J. Patel,Fumiko Shimizu,Alexander Bolaender,Chenghua Yang,Palak Panchal,Mohammad F. Farooq,Sarah Kishinevsky,Shanu Modi,Oscar Lin,Feixia Chu,Sujata Patil,Hediye Erdjument-Bromage,Pat Zanzonico,Clifford A. Hudis,Lorenz Studer,Gail J. Roboz,Ethel Cesarman,Leandro Cerchietti,Ross L. Levine,Ari Melnick,Steven M. Larson,Jason S. Lewis,Monica L. Guzman,Gabriela Chiosis,Gabriela Chiosis +43 more
TL;DR: It is found that under conditions of stress, such as malignant transformation fuelled by MYC, the chaperome becomes biochemically ‘rewired’ to form a network of stable, survival-facilitating, high-molecular-weight complexes.
Journal ArticleDOI
Ex vivo treatment response of primary tumors and/or associated metastases for preclinical and clinical development of therapeutics.
Adriana D. Corben,Mohammad M. Uddin,Brooke Crawford,Mohammad F. Farooq,Shanu Modi,John F. Gerecitano,Gabriela Chiosis,Mary L. Alpaugh +7 more
TL;DR: This work has developed an ex vivo (fresh tissue sectioning) technique which allows for the direct assessment of treatment response for preclinical and clinical therapeutics development and maintains tissue integrity and cellular architecture within the tumor cell/microenvironment context throughout treatment response providing a more precise means to assess drug efficacy.