M
Mohammad Hashemi
Researcher at Mashhad University of Medical Sciences
Publications - 522
Citations - 10253
Mohammad Hashemi is an academic researcher from Mashhad University of Medical Sciences. The author has contributed to research in topics: Genotype & Odds ratio. The author has an hindex of 42, co-authored 486 publications receiving 8506 citations. Previous affiliations of Mohammad Hashemi include Golestan University & Iran University of Medical Sciences.
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Journal ArticleDOI
Autophagy and apoptosis dysfunction in neurodegenerative disorders.
Saeid Ghavami,Shahla Shojaei,Behzad Yeganeh,Sudharsana R. Ande,Jaganmohan Reddy Jangamreddy,Maryam Mehrpour,Jonas Christoffersson,Wiem Chaabane,Adel Rezaei Moghadam,Hessam H. Kashani,Mohammad Hashemi,Ali Akbar Owji,Marek J. Łos +12 more
TL;DR: In this article, the authors provide a brief introduction to autophagy and apoptosis pathways focusing on the role of mitochondria and lysosomes, and discuss different ways that autophag and apoptotic modulation may be employed for therapeutic intervention during the maintenance of neurodegenerative disorders.
Journal ArticleDOI
Apoptosis and cancer: mutations within caspase genes
Saeid Ghavami,Mohammad Hashemi,Sudharsana R. Ande,Behzad Yeganeh,Wenyan Xiao,Mehdi Eshraghi,Christine J Bus,Kamran Kadkhoda,Emilia Wiechec,Andrew J. Halayko,Marek Los +10 more
TL;DR: This review gives an overview of the role of caspases, their natural modulators like IAPs, FLIPs, and Smac/Diablo in apoptosis and upon inactivation, and also in cancer development and some of the direct activators of procaspase-3.
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S100A8/A9 at low concentration promotes tumor cell growth via RAGE ligation and MAP kinase-dependent pathway
Saeid Ghavami,Iran Rashedi,Brian M. Dattilo,Mehdi Eshraghi,Walter J. Chazin,Mohammad Hashemi,Sebastian Wesselborg,Claus Kerkhoff,Marek Los +8 more
TL;DR: The data indicate that S100A8/A9‐promoted cell growth occurs through RAGE signaling and activation of NF‐κB, which is mediated via RAGE ligation.
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S100A8/A9 induces autophagy and apoptosis via ROS-mediated cross-talk between mitochondria and lysosomes that involves BNIP3.
Saeid Ghavami,Mehdi Eshragi,Sudharsana R. Ande,Walter J. Chazin,Thomas Klonisch,Andrew J. Halayko,Karol D. McNeill,Mohammad Hashemi,Claus Kerkhoff,Marek Los +9 more
TL;DR: The data indicate that S100A8/A9-promoted cell death occurs through the cross-talk of mitochondria and lysosomes via ROS and the process involves BNIP3.
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Whey protein isolate/cellulose nanofibre/TiO 2 nanoparticle/rosemary essential oil nanocomposite film: Its effect on microbial and sensory quality of lamb meat and growth of common foodborne pathogenic bacteria during refrigeration
TL;DR: Based on the results of this study, the edible nanocomposite films were effective in preserving the microbial and sensory qualities of lamb meat; therefore, this application is recommended in meat especially red meat.