M
Mohammad Reza Karimzadeh
Publications - 17
Citations - 446
Mohammad Reza Karimzadeh is an academic researcher. The author has contributed to research in topics: Cancer & microRNA. The author has an hindex of 8, co-authored 17 publications receiving 237 citations.
Papers
More filters
Journal ArticleDOI
Circular RNAs and gastrointestinal cancers: Epigenetic regulators with a prognostic and therapeutic role.
Parisa Naeli,Mohammad Hossein Pourhanifeh,Mohammad Reza Karimzadeh,Zahra Shabaninejad,Zahra Shabaninejad,Ahmad Movahedpour,Hossein Tarrahimofrad,Hamid Reza Mirzaei,Hassan Hassani Bafrani,Amir Savardashtaki,Hamed Mirzaei,Michael R. Hamblin +11 more
TL;DR: The properties and biogenesis of circRNAs are described, recent reports about circRNA functions, expression status, and their potential to be used as biomarkers in GI cancers including, gastric cancer, colorectal cancer, esophageal cancers, hepatocellular carcinoma, gallbladder cancer and pancreatic cancer are summarized.
Journal ArticleDOI
Mechanisms underlying low-clinical responses to PD-1/PD-L1 blocking antibodies in immunotherapy of cancer: a key role of exosomal PD-L1.
Zi Yin,Min Yu,Tingting Ma,Chuanzhao Zhang,Shanzhou Huang,Mohammad Reza Karimzadeh,Amir Abaas Momtazi-Borojeni,Sheng Chen +7 more
TL;DR: In this article, the role of exosomal PDL-1 in the therapeutic resistance to anti-PD-1/PD-L1 treatment was reviewed. But, despite impressive treatment outcomes, some patients show poor response to PD-1 and PD-L 1 blockade.
Journal ArticleDOI
The role of miR-146a in viral infection.
Javid Sadri Nahand,Mohammad Reza Karimzadeh,Maria Nezamnia,Maryam Fatemipour,Alireza Khatami,Sogol Jamshidi,Mohsen Moghoofei,Mohammad Taghizadieh,Sarah Hajighadimi,Alimohammad Shafiee,Mohammad Sadeghian,Farah Bokharaei-Salim,Hamed Mirzaei +12 more
TL;DR: Recent reports regarding miR‐146a expression levels, target genes, function, and contributing role in the pathogenesis of the viral infection are discussed to provide a clue to develop the new therapeutic and preventive strategies for viral disease in the future.
Journal ArticleDOI
Autophagy in cancers including brain tumors: role of MicroRNAs
Mohammad Hossein Pourhanifeh,Maryam Mahjoubin-Tehran,Mohammad Reza Karimzadeh,Hamid Reza Mirzaei,Zahra Sadat Razavi,Amirhossein Sahebkar,Nayyerehsadat Hosseini,Hamed Mirzaei,Michael R. Hamblin +8 more
TL;DR: A deeper understanding of the underlying molecular targets of miRNAs, and their function in autophagy pathways could contribute to the development of new treatment methods for patients with brain tumors.
Journal ArticleDOI
Modulatory effects of curcumin on the atherogenic activities of inflammatory monocytes: Evidence from in vitro and animal models of human atherosclerosis.
Saeed Mohammadian Haftcheshmeh,Mohammad Reza Karimzadeh,Sara Azhdari,Parviz Vahedi,Elham Abdollahi,Amir Abbas Momtazi-Borojeni +5 more
TL;DR: It is shown that curcumin can exert antiatherosclerotic effect through inhibiting the atherogenic properties of monocytes, including inflammatory cytokine production, adhesion, and transendothelial migration, as well as intracellular cholesterol accumulation.