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Mohammad Reza Karimzadeh

Publications -  17
Citations -  446

Mohammad Reza Karimzadeh is an academic researcher. The author has contributed to research in topics: Cancer & microRNA. The author has an hindex of 8, co-authored 17 publications receiving 237 citations.

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Circular RNAs and gastrointestinal cancers: Epigenetic regulators with a prognostic and therapeutic role.

TL;DR: The properties and biogenesis of circRNAs are described, recent reports about circRNA functions, expression status, and their potential to be used as biomarkers in GI cancers including, gastric cancer, colorectal cancer, esophageal cancers, hepatocellular carcinoma, gallbladder cancer and pancreatic cancer are summarized.
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Mechanisms underlying low-clinical responses to PD-1/PD-L1 blocking antibodies in immunotherapy of cancer: a key role of exosomal PD-L1.

TL;DR: In this article, the role of exosomal PDL-1 in the therapeutic resistance to anti-PD-1/PD-L1 treatment was reviewed. But, despite impressive treatment outcomes, some patients show poor response to PD-1 and PD-L 1 blockade.
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The role of miR-146a in viral infection.

TL;DR: Recent reports regarding miR‐146a expression levels, target genes, function, and contributing role in the pathogenesis of the viral infection are discussed to provide a clue to develop the new therapeutic and preventive strategies for viral disease in the future.
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Autophagy in cancers including brain tumors: role of MicroRNAs

TL;DR: A deeper understanding of the underlying molecular targets of miRNAs, and their function in autophagy pathways could contribute to the development of new treatment methods for patients with brain tumors.
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Modulatory effects of curcumin on the atherogenic activities of inflammatory monocytes: Evidence from in vitro and animal models of human atherosclerosis.

TL;DR: It is shown that curcumin can exert antiatherosclerotic effect through inhibiting the atherogenic properties of monocytes, including inflammatory cytokine production, adhesion, and transendothelial migration, as well as intracellular cholesterol accumulation.