M
Mojgan Djavaheri-Mergny
Researcher at University of Bordeaux
Publications - 65
Citations - 16720
Mojgan Djavaheri-Mergny is an academic researcher from University of Bordeaux. The author has contributed to research in topics: Autophagy & Programmed cell death. The author has an hindex of 32, co-authored 62 publications receiving 14926 citations. Previous affiliations of Mojgan Djavaheri-Mergny include University of Paris & Curie Institute.
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Book ChapterDOI
Autophagy and Autophagic Cell Death
TL;DR: The role of autophagy as a stress response mechanism can protect cancer cells from various insults and can eliminate cancer cells by triggering autophagic cell death, and the importance of tumor suppressor molecules in the stimulation of Autophagy is uncovered.
Journal ArticleDOI
Activation of the Ataxia Telangiectasia Mutated/Autophagy pathway by a G-quadruplex ligand links senescence with apoptosis
Jennifer Beauvarlet,Jean-Louis Mergny,Mojgan Djavaheri-Mergny,Mojgan Djavaheri-Mergny,Mojgan Djavaheri-Mergny +4 more
TL;DR: It is reported that the G4 ligand 20A promotes senescence in cancer cells through Ataxia Telangiectasia Mutated and autophagy activation, and inhibition of both pathways directs cells to apoptosis, positioning ATM/autophagy axis as a linchpin between senescences and apoptosis.
Book ChapterDOI
The Complex Crosstalk Between Autophagy and ROS Signalling Pathways
TL;DR: The regulation of inflammatory responses by autophagy is discussed as a consequence of the interplay of Autophagy and ROS signaling pathways.
Journal ArticleDOI
G-quadruplex ligands as potent regulators of lysosomes
Lucille Ferret,Karla Maria Alvarez-Valadez,Jennifer Rivière,Alexandra Muller,Natalia Bohalova,Lionel Guittat,Václav Brázda,Guido Kroemer,Jean-Louis Mergny,Mojgan Djavaheri-Mergny +9 more
TL;DR: In this paper , Guanine-quadruplex structures (G4) are unusual nucleic acid conformations formed by guanine-rich DNA and RNA sequences and known to control gene expression mechanisms, from transcription to protein synthesis.