Monica Pujol Canadell

TL;DR: This is the first study to identify radiation-induced human protein signatures in vivo using the humanized mouse model and develop a protein panel which could be used for the rapid assessment of absorbed dose 3 days after radiation exposure.

TL;DR: The results showed that even a small percentage of neutrons in a mixed field can lead to high biological responses with implications for accurate biodosimetry, triage and medical managements of exposed populations.

TL;DR: A high-throughput micronucleus assay with automated scanning and imaging software on ex-vivo irradiated human lymphocytes is used to reconstruct partial-body and/or neutron exposure and estimate separately the photon and neutron doses in a mixed exposure, demonstrating a proof-of-principle for the proposed approach of high- Throughput reconstruction of clinically-relevant complex radiation exposure scenarios.

TL;DR: The results suggest that the FAST-DOSE bioassay has large potential as a useful diagnostic tool for rapid and reliable screening of potentially exposed individuals to aid early triage decisions within the first week post-exposure.

TL;DR: In this paper, the authors employed untargeted metabolomic methods to develop a biosignature in urine and serum from C57BL/6 mice to address radiation quality issues.