M
Moumita Ghosh
Researcher at University of Colorado Denver
Publications - 49
Citations - 1916
Moumita Ghosh is an academic researcher from University of Colorado Denver. The author has contributed to research in topics: Progenitor cell & Phospholipase A2. The author has an hindex of 23, co-authored 44 publications receiving 1708 citations. Previous affiliations of Moumita Ghosh include National Jewish Health & Indian Institute of Chemical Biology.
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Journal ArticleDOI
Properties of the Group IV phospholipase A2 family.
TL;DR: Group IV phospholipase A2 alpha, the most extensively studied Group IV PLA2, is widely expressed in mammalian cells and mediates the production of functionally diverse lipid products in response to extracellular stimuli.
Journal ArticleDOI
Regulation of Cytosolic Phospholipase A2 Activation and Cyclooxygenase 2 Expression in Macrophages by the β-Glucan Receptor
Saritha Suram,Gordon D. Brown,Moumita Ghosh,Siamon Gordon,Robyn Loper,Philip R. Taylor,Shizuo Akira,Satoshi Uematsu,David L. Williams,Christina C. Leslie +9 more
TL;DR: The results suggest that cytosolic phospholipase A2 activation triggered by the β-glucan component of yeast is dependent on the immunoreceptor tyrosine-based activation motif-like domain of dectin-1 and activation of Syk kinase, whereas both TLR2 and SyK kinase regulate COX2 expression.
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TNF-α Inhibits Macrophage Clearance of Apoptotic Cells via Cytosolic Phospholipase A2 and Oxidant-Dependent Mechanisms
Kathleen A. McPhillips,William J. Janssen,Moumita Ghosh,Aideen Byrne,Shyra J. Gardai,Linda K. Remigio,Donna L. Bratton,Jihee L. Kang,Peter M. Henson +8 more
TL;DR: The data suggest that macrophages in a TNF-α- and oxidant-rich inflammatory environment are less able to remove apoptotic cells and, thereby, may contribute to the local intensity of the inflammatory response.
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Enzymatic Properties of Human Cytosolic Phospholipase A2γ
TL;DR: The enzymatic properties of cytosolic phospholipase A2γ (cPLA2γ), an isoform of 85-kDa group IV cPLA2α (c PLA2α) were studied in vitro and when the enzyme was expressed in cells, resulting in results primarily in arachidonic acid release.
Journal ArticleDOI
Context-Dependent Differentiation of Multipotential Keratin 14–Expressing Tracheal Basal Cells
Moumita Ghosh,Heather M. Brechbuhl,Russell W. Smith,Bilan Li,Douglas A. Hicks,Timothy Titchner,Christine M. Runkle,Susan D. Reynolds +7 more
TL;DR: Lineage tracing of tracheobronchial basal cells after naphthalene injury or in the postnatal period demonstrated that basal cells were MP progenitors for Clara-like and ciliated cells, and it was shown that sK14EC were unipotential in the normal epithelium and MP after NA.