M
Muhammad Shehroz
Researcher at Virtual University of Pakistan
Publications - 14
Citations - 228
Muhammad Shehroz is an academic researcher from Virtual University of Pakistan. The author has contributed to research in topics: Genome & Reverse vaccinology. The author has an hindex of 6, co-authored 13 publications receiving 111 citations. Previous affiliations of Muhammad Shehroz include Abdul Wali Khan University Mardan & University of the Sciences.
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Journal ArticleDOI
Immunoinformatics-Aided Design and Evaluation of a Potential Multi-Epitope Vaccine against Klebsiella Pneumoniae.
Hamza Arshad Dar,Tahreem Zaheer,Muhammad Shehroz,Nimat Ullah,Kanwal Naz,Syed Aun Muhammad,Tianyu Zhang,Amjad Ali +7 more
TL;DR: The computer-aided analyses performed in this study imply that the designed multi-epitope vaccine can elicit specific immune responses against K. pneumoniae, and wet lab validation is necessary to further verify the effectiveness of this proposed vaccine candidate.
Journal ArticleDOI
Vaccine design from the ensemble of surface glycoprotein epitopes of SARS-CoV-2: An immunoinformatics approach
Noor Naemah Abdul Rahman,Fawad Ali,Zarrin Basharat,Muhammad Shehroz,Muhammad Kazim Khan,Philippe Jeandet,Eugenie Nepovimova,Kamil Kuca,Haroon Khan +8 more
TL;DR: In conclusion, C1 was the best vaccine candidate among all designed constructs to elicit an immune response SARS-CoV-2 and combat the coronavirus disease (COVID-19).
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Computer-aided drug design against spike glycoprotein of SARS-CoV-2 to aid COVID-19 treatment.
TL;DR: The RBM region of S interacts with Angiotensin Converting Enzyme 2 (ACE2) receptor and Glucose Regulated Protein 78 (GRP78) to mediate viral entry and can prevent its internalization in cell using ACE2 and GRP78 receptor.
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Anti-COVID-19 multi-epitope vaccine designs employing global viral genome sequences.
Tahreem Zaheer,Maaz Waseem,Walifa Waqar,Hamza Arshad Dar,Muhammad Shehroz,Kanwal Naz,Zaara Ishaq,Tahir Ahmad,Nimat Ullah,Syeda Marriam Bakhtiar,Syed Aun Muhammad,Amjad Ali +11 more
TL;DR: In silico analyses suggest that the proposed multi-epitope vaccine can effectively evoke an immune response against SARS-CoV-2 strains and is likely to be antigenic and non-allergenic.
Journal ArticleDOI
Potential druggable proteins and chimeric vaccine construct prioritization against Brucella melitensis from species core genome data.
M. Aslam,Muhammad Shehroz,Hizbullah,Mohibullah Shah,Munazza Ali Khan,Sahib Gul Afridi,Asifullah Khan +6 more
TL;DR: The molecular docking and MD simulation analyses ensured stable molecular interaction of a finally prioritized vaccine construct with human immune cells receptors and potential chimeric vaccine constructs were generated from lead T and B-cell overlapped epitopes in combination with immune enhancer adjuvants and linkers sequences.