M
Mustapha Oulad-Abdelghani
Researcher at Collège de France
Publications - 15
Citations - 2147
Mustapha Oulad-Abdelghani is an academic researcher from Collège de France. The author has contributed to research in topics: Retinoic acid & Homeobox. The author has an hindex of 14, co-authored 15 publications receiving 2080 citations. Previous affiliations of Mustapha Oulad-Abdelghani include French Institute of Health and Medical Research.
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Journal ArticleDOI
Heterochromatin Formation in Mammalian Cells: Interaction between Histones and HP1 Proteins
Anders Lade Nielsen,Mustapha Oulad-Abdelghani,José A. Ortiz,Eumorphia Remboutsika,Pierre Chambon,Régine Losson +5 more
TL;DR: Results define a novel function for the conserved CD and suggest that HP1 self-association and histone binding may play a crucial role in HP1-mediated heterochromatin assembly.
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Interaction with members of the heterochromatin protein 1 (HP1) family and histone deacetylation are differentially involved in transcriptional silencing by members of the TIF1 family.
Anders Lade Nielsen,José A. Ortiz,Jun You,Mustapha Oulad-Abdelghani,Ruben Khechumian,Anne Gansmuller,Pierre Chambon,Régine Losson +7 more
TL;DR: An association of TIF1β with both heterochromatin and euchromatin in interphase nuclei is reported and it is shown that trichostatin A, an inhibitor of histone deacetylases, can interfere with both Tif1 and HP1 silencing.
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AP-2.2, a novel gene related to AP-2, is expressed in the forebrain, limbs and face during mouse embryogenesis
Claire Chazaud,Mustapha Oulad-Abdelghani,Philippe Bouillet,Didier Decimo,Pierre Chambon,Pascal Dollé +5 more
TL;DR: The in situ hybridization pattern of expression of AP-2.2 transcripts during mouse embryogenesis is reported, which shows the gene is expressed in several embryonic areas whose development can be affected by retinoids, such as the forebrain, face and limb buds.
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STRA8-deficient spermatocytes initiate, but fail to complete, meiosis and undergo premature chromosome condensation
Manuel Mark,Hugues Jacobs,Mustapha Oulad-Abdelghani,Christine Dennefeld,Betty Féret,Nadège Vernet,Carmen-Alina Codreanu,Pierre Chambon,Norbert B. Ghyselinck +8 more
TL;DR: It is proposed that, in preleptotene spermatocytes, STRA8 is involved in the process that leads to stable commitment to the meiotic cell cycle.
Journal ArticleDOI
Efficient cloning of cDNAs of retinoic acid-responsive genes in P19 embryonal carcinoma cells and characterization of a novel mouse gene, Stra1 (mouse LERK-2/Eplg2).
Philippe Bouillet,Mustapha Oulad-Abdelghani,Serge Vicaire,Jean-Marie Garnier,Brigitte Schuhbaur,Pascal Dollé,Pierre Chambon +6 more
TL;DR: An efficient differential subtractive hybridization cloning strategy was used to identify additional RA-responsive genes in P19 cells and describes the sequence and expression pattern in mouse embryos and adult tissues of one of these novel RA-inducible genes, Stra1, and shows that it corresponds to the mouse ligand for the Cek5 receptor protein-tyrosine kinase.